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Protection against SARS-CoV-2 transmission by a parenteral prime—Intranasal boost vaccine strategy

BACKGROUND: Licensed vaccines against SARS-CoV-2 effectively protect against severe disease, but display incomplete protection against virus transmission. Mucosal vaccines providing immune responses in the upper airways are one strategy to protect against transmission. METHODS: We administered Spike...

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Detalles Bibliográficos
Autores principales: Christensen, Dennis, Polacek, Charlotta, Sheward, Daniel J., Hanke, Leo, Moliner-Morro, Ainhoa, McInerney, Gerald, Murrell, Ben, Hartmann, Katrine Top, Jensen, Henrik Elvang, Jungersen, Gregers, Illigen, Kristin, Isling, Louise Krag, Jensen, Rune Fledelius, Hansen, Julia Sid, Rosenkrands, Ida, Fernandez-Antunez, Carlota, Ramirez, Santseharay, Follmann, Frank, Bukh, Jens, Pedersen, Gabriel Kristian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9448948/
https://www.ncbi.nlm.nih.gov/pubmed/36088218
http://dx.doi.org/10.1016/j.ebiom.2022.104248