Cargando…
Protection against SARS-CoV-2 transmission by a parenteral prime—Intranasal boost vaccine strategy
BACKGROUND: Licensed vaccines against SARS-CoV-2 effectively protect against severe disease, but display incomplete protection against virus transmission. Mucosal vaccines providing immune responses in the upper airways are one strategy to protect against transmission. METHODS: We administered Spike...
Autores principales: | Christensen, Dennis, Polacek, Charlotta, Sheward, Daniel J., Hanke, Leo, Moliner-Morro, Ainhoa, McInerney, Gerald, Murrell, Ben, Hartmann, Katrine Top, Jensen, Henrik Elvang, Jungersen, Gregers, Illigen, Kristin, Isling, Louise Krag, Jensen, Rune Fledelius, Hansen, Julia Sid, Rosenkrands, Ida, Fernandez-Antunez, Carlota, Ramirez, Santseharay, Follmann, Frank, Bukh, Jens, Pedersen, Gabriel Kristian |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9448948/ https://www.ncbi.nlm.nih.gov/pubmed/36088218 http://dx.doi.org/10.1016/j.ebiom.2022.104248 |
Ejemplares similares
-
SARS-CoV-2 spike HexaPro formulated in aluminium hydroxide and administered in an accelerated vaccination schedule partially protects Syrian Hamsters against viral challenge despite low neutralizing antibody responses
por: Christensen, Dennis, et al.
Publicado: (2023) -
Picomolar SARS-CoV-2 Neutralization Using Multi-Arm PEG Nanobody Constructs
por: Moliner-Morro, Ainhoa, et al.
Publicado: (2020) -
An alpaca nanobody neutralizes SARS-CoV-2 by blocking receptor interaction
por: Hanke, Leo, et al.
Publicado: (2020) -
A review of the human vs. porcine female genital tract and associated immune system in the perspective of using minipigs as a model of human genital Chlamydia infection
por: Lorenzen, Emma, et al.
Publicado: (2015) -
A bispecific monomeric nanobody induces spike trimer dimers and neutralizes SARS-CoV-2 in vivo
por: Hanke, Leo, et al.
Publicado: (2022)