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25 (OH) D3 levels, incidence and recurrence of different clinical forms of benig paroxysmal positional vertigo()

INTRODUCTION: Benign paroxysmal positional vertigo is the most common cause of dizziness in the general population. It is a condition with potential impact of reduced levels of vitamin D on its recurrent attacks. OBJECTIVES: The aim of this study was to measure the serum levels of 25-hydroxyvitamin...

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Autores principales: Maslovara, Sinisa, Butkovic Soldo, Silva, Sestak, Anamarija, Milinkovic, Katarina, Rogic-Namacinski, Jasna, Soldo, Anamarija
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9449225/
https://www.ncbi.nlm.nih.gov/pubmed/28655524
http://dx.doi.org/10.1016/j.bjorl.2017.05.007
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author Maslovara, Sinisa
Butkovic Soldo, Silva
Sestak, Anamarija
Milinkovic, Katarina
Rogic-Namacinski, Jasna
Soldo, Anamarija
author_facet Maslovara, Sinisa
Butkovic Soldo, Silva
Sestak, Anamarija
Milinkovic, Katarina
Rogic-Namacinski, Jasna
Soldo, Anamarija
author_sort Maslovara, Sinisa
collection PubMed
description INTRODUCTION: Benign paroxysmal positional vertigo is the most common cause of dizziness in the general population. It is a condition with potential impact of reduced levels of vitamin D on its recurrent attacks. OBJECTIVES: The aim of this study was to measure the serum levels of 25-hydroxyvitamin D3 (25-OH D3) in patients with benign paroxysmal positional vertigo and determine whether there is a difference in the serum levels of vitamin D3 between patients with and without recurrence, as well as between the different clinical forms of benign paroxysmal positional vertigo. METHODS: The study included 40 patients who came to the regular medical examination, diagnosed with posterior canal-benign paroxysmal positional vertigo based on the positive Dix-Hallpike's test. All patients underwent Epley manoeuvre after the diagnosis. Patients were classified according to current guidelines for levels of vitamin D3 in the serum in three groups: the deficiency, insufficiency and adequate level. RESULTS: The average serum level of 25-OH D3 among respondents was 20.78 ng/mL, indicating a lack or insufficiency of the aforementioned 25-OH D3. According to the levels of 25-OH D3, most patients suffer from deficiency (47.5%). 7 (17.5%) respondents had adequate blood level of 25-OH D3, and 14 (35%) respondents suffer from insufficiency. A significant difference was not found in the serum level of 25-OH D3 between patients with and without benign paroxysmal positional vertigo recurrence. There was a significant difference in the serum levels of 25-OH D3 in comparison to the clinical form of the disease. Lower 25-OH D3 values were found in patients with canalithiasis compared to those with cupulolithiasis. CONCLUSIONS: There were no significant differences in the vitamin D3 serum level in patients with and without recurrence. The study showed a low level of serum vitamin D3 in most patients, indicating the need for supplemental therapy.
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spelling pubmed-94492252022-09-09 25 (OH) D3 levels, incidence and recurrence of different clinical forms of benig paroxysmal positional vertigo() Maslovara, Sinisa Butkovic Soldo, Silva Sestak, Anamarija Milinkovic, Katarina Rogic-Namacinski, Jasna Soldo, Anamarija Braz J Otorhinolaryngol Original Article INTRODUCTION: Benign paroxysmal positional vertigo is the most common cause of dizziness in the general population. It is a condition with potential impact of reduced levels of vitamin D on its recurrent attacks. OBJECTIVES: The aim of this study was to measure the serum levels of 25-hydroxyvitamin D3 (25-OH D3) in patients with benign paroxysmal positional vertigo and determine whether there is a difference in the serum levels of vitamin D3 between patients with and without recurrence, as well as between the different clinical forms of benign paroxysmal positional vertigo. METHODS: The study included 40 patients who came to the regular medical examination, diagnosed with posterior canal-benign paroxysmal positional vertigo based on the positive Dix-Hallpike's test. All patients underwent Epley manoeuvre after the diagnosis. Patients were classified according to current guidelines for levels of vitamin D3 in the serum in three groups: the deficiency, insufficiency and adequate level. RESULTS: The average serum level of 25-OH D3 among respondents was 20.78 ng/mL, indicating a lack or insufficiency of the aforementioned 25-OH D3. According to the levels of 25-OH D3, most patients suffer from deficiency (47.5%). 7 (17.5%) respondents had adequate blood level of 25-OH D3, and 14 (35%) respondents suffer from insufficiency. A significant difference was not found in the serum level of 25-OH D3 between patients with and without benign paroxysmal positional vertigo recurrence. There was a significant difference in the serum levels of 25-OH D3 in comparison to the clinical form of the disease. Lower 25-OH D3 values were found in patients with canalithiasis compared to those with cupulolithiasis. CONCLUSIONS: There were no significant differences in the vitamin D3 serum level in patients with and without recurrence. The study showed a low level of serum vitamin D3 in most patients, indicating the need for supplemental therapy. Elsevier 2017-06-11 /pmc/articles/PMC9449225/ /pubmed/28655524 http://dx.doi.org/10.1016/j.bjorl.2017.05.007 Text en © 2017 Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial. Published by Elsevier Editora Ltda. https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Original Article
Maslovara, Sinisa
Butkovic Soldo, Silva
Sestak, Anamarija
Milinkovic, Katarina
Rogic-Namacinski, Jasna
Soldo, Anamarija
25 (OH) D3 levels, incidence and recurrence of different clinical forms of benig paroxysmal positional vertigo()
title 25 (OH) D3 levels, incidence and recurrence of different clinical forms of benig paroxysmal positional vertigo()
title_full 25 (OH) D3 levels, incidence and recurrence of different clinical forms of benig paroxysmal positional vertigo()
title_fullStr 25 (OH) D3 levels, incidence and recurrence of different clinical forms of benig paroxysmal positional vertigo()
title_full_unstemmed 25 (OH) D3 levels, incidence and recurrence of different clinical forms of benig paroxysmal positional vertigo()
title_short 25 (OH) D3 levels, incidence and recurrence of different clinical forms of benig paroxysmal positional vertigo()
title_sort 25 (oh) d3 levels, incidence and recurrence of different clinical forms of benig paroxysmal positional vertigo()
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9449225/
https://www.ncbi.nlm.nih.gov/pubmed/28655524
http://dx.doi.org/10.1016/j.bjorl.2017.05.007
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