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Camels’ biological fluids contained nanobodies: promising avenue in cancer therapy

Cancer is a major health concern and accounts for one of the main causes of death worldwide. Innovative strategies are needed to aid in the diagnosis and treatment of different types of cancers. Recently, there has been an evolving interest in utilizing nanobodies of camel origin as therapeutic tool...

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Autores principales: Al-Numair, Nouf S., Theyab, Abdulrahman, Alzahrani, Faisal, Shams, Anwar M., Al-Anazi, Ibrahim O., Oyouni, Atif Abdulwahab A., Al-Amer, Osama M., Mavromatis, Charalampos, Saadeldin, Islam M., Abdali, Wed A., Hawsawi, Yousef M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9449263/
https://www.ncbi.nlm.nih.gov/pubmed/36071488
http://dx.doi.org/10.1186/s12935-022-02696-7
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author Al-Numair, Nouf S.
Theyab, Abdulrahman
Alzahrani, Faisal
Shams, Anwar M.
Al-Anazi, Ibrahim O.
Oyouni, Atif Abdulwahab A.
Al-Amer, Osama M.
Mavromatis, Charalampos
Saadeldin, Islam M.
Abdali, Wed A.
Hawsawi, Yousef M.
author_facet Al-Numair, Nouf S.
Theyab, Abdulrahman
Alzahrani, Faisal
Shams, Anwar M.
Al-Anazi, Ibrahim O.
Oyouni, Atif Abdulwahab A.
Al-Amer, Osama M.
Mavromatis, Charalampos
Saadeldin, Islam M.
Abdali, Wed A.
Hawsawi, Yousef M.
author_sort Al-Numair, Nouf S.
collection PubMed
description Cancer is a major health concern and accounts for one of the main causes of death worldwide. Innovative strategies are needed to aid in the diagnosis and treatment of different types of cancers. Recently, there has been an evolving interest in utilizing nanobodies of camel origin as therapeutic tools against cancer. Nanotechnology uses nanobodies an emerging attractive field that provides promises to researchers in advancing different scientific sectors including medicine and oncology. Nanobodies are characteristically small-sized biologics featured with the ability for deep tissue penetration and dissemination and harbour high stability at high pH and temperatures. The current review highlights the potential use of nanobodies that are naturally secreted in camels’ biological fluids, both milk and urine, in the development of nanotechnology-based therapy for treating different typesQuery of cancers and other diseases. Moreover, the role of nano proteomics in the invention of novel therapeutic agents specifically used for cancer intervention is also illustrated.
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spelling pubmed-94492632022-09-07 Camels’ biological fluids contained nanobodies: promising avenue in cancer therapy Al-Numair, Nouf S. Theyab, Abdulrahman Alzahrani, Faisal Shams, Anwar M. Al-Anazi, Ibrahim O. Oyouni, Atif Abdulwahab A. Al-Amer, Osama M. Mavromatis, Charalampos Saadeldin, Islam M. Abdali, Wed A. Hawsawi, Yousef M. Cancer Cell Int Review Cancer is a major health concern and accounts for one of the main causes of death worldwide. Innovative strategies are needed to aid in the diagnosis and treatment of different types of cancers. Recently, there has been an evolving interest in utilizing nanobodies of camel origin as therapeutic tools against cancer. Nanotechnology uses nanobodies an emerging attractive field that provides promises to researchers in advancing different scientific sectors including medicine and oncology. Nanobodies are characteristically small-sized biologics featured with the ability for deep tissue penetration and dissemination and harbour high stability at high pH and temperatures. The current review highlights the potential use of nanobodies that are naturally secreted in camels’ biological fluids, both milk and urine, in the development of nanotechnology-based therapy for treating different typesQuery of cancers and other diseases. Moreover, the role of nano proteomics in the invention of novel therapeutic agents specifically used for cancer intervention is also illustrated. BioMed Central 2022-09-07 /pmc/articles/PMC9449263/ /pubmed/36071488 http://dx.doi.org/10.1186/s12935-022-02696-7 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Review
Al-Numair, Nouf S.
Theyab, Abdulrahman
Alzahrani, Faisal
Shams, Anwar M.
Al-Anazi, Ibrahim O.
Oyouni, Atif Abdulwahab A.
Al-Amer, Osama M.
Mavromatis, Charalampos
Saadeldin, Islam M.
Abdali, Wed A.
Hawsawi, Yousef M.
Camels’ biological fluids contained nanobodies: promising avenue in cancer therapy
title Camels’ biological fluids contained nanobodies: promising avenue in cancer therapy
title_full Camels’ biological fluids contained nanobodies: promising avenue in cancer therapy
title_fullStr Camels’ biological fluids contained nanobodies: promising avenue in cancer therapy
title_full_unstemmed Camels’ biological fluids contained nanobodies: promising avenue in cancer therapy
title_short Camels’ biological fluids contained nanobodies: promising avenue in cancer therapy
title_sort camels’ biological fluids contained nanobodies: promising avenue in cancer therapy
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9449263/
https://www.ncbi.nlm.nih.gov/pubmed/36071488
http://dx.doi.org/10.1186/s12935-022-02696-7
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