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Effect of add-on alpha lipoic acid on psychopathology in patients with treatment-resistant schizophrenia: a pilot randomized double-blind placebo-controlled trial

RATIONALE: Alpha lipoic acid is known to reverse NMDA receptor hypofunction in addition to dopamine receptor blockade activity. It also enhances neurotrophic factors and has antioxidant potential. These properties combined together may be beneficial for treatment-resistant schizophrenia (TRS). OBJEC...

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Detalles Bibliográficos
Autores principales: Mishra, Archana, Reeta, K. H., Sarangi, Sudhir Chandra, Maiti, Rituparna, Sood, Mamta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9449282/
https://www.ncbi.nlm.nih.gov/pubmed/36069950
http://dx.doi.org/10.1007/s00213-022-06225-2