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PD-1(+) CD4 T cell immune response is mediated by HIF-1α/NFATc1 pathway after P. yoelii infection
The morbidity and mortality of malaria are still high. Programmed cell death-1(PD-1) is an important co-inhibitory factor and CD8 T cells with PD-1 were reported to be exhausted cells. It remains unknown what the role of CD4 T cells expressing PD-1 is and what the upstream regulating molecules of PD...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9449323/ https://www.ncbi.nlm.nih.gov/pubmed/36091043 http://dx.doi.org/10.3389/fimmu.2022.942862 |