PD-1(+) CD4 T cell immune response is mediated by HIF-1α/NFATc1 pathway after P. yoelii infection

The morbidity and mortality of malaria are still high. Programmed cell death-1(PD-1) is an important co-inhibitory factor and CD8 T cells with PD-1 were reported to be exhausted cells. It remains unknown what the role of CD4 T cells expressing PD-1 is and what the upstream regulating molecules of PD...

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Detalles Bibliográficos
Autores principales: Wei, Haixia, Xie, Anqi, Li, Jiajie, Fang, Chao, Liu, Lin, Xing, Junmin, Shi, Feihu, Mo, Feng, Chen, Dianhui, Xie, Hongyan, Yang, Quan, Pan, Xingfei, Tang, Xiaoping, Huang, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9449323/
https://www.ncbi.nlm.nih.gov/pubmed/36091043
http://dx.doi.org/10.3389/fimmu.2022.942862

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