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Biliary Intraepithelial Neoplasia With Gallbladder Adenoma and Cirrhosis: A Case Report
Biliary intraepithelial neoplasia (BilIN) is a precursor lesion of cholangiocarcinoma that has been rarely reported. The present study reports a 56-year-old male with low-grade BilIN of the bile ducts and the cystic duct margin. Stent exchange endoscopy demonstrated an irregular, intraductal mass ex...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9449331/ https://www.ncbi.nlm.nih.gov/pubmed/36106242 http://dx.doi.org/10.7759/cureus.27780 |
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author | Chen, William J Wolff, Evan Varma, Chintalapati R Shoela, Ramy |
author_facet | Chen, William J Wolff, Evan Varma, Chintalapati R Shoela, Ramy |
author_sort | Chen, William J |
collection | PubMed |
description | Biliary intraepithelial neoplasia (BilIN) is a precursor lesion of cholangiocarcinoma that has been rarely reported. The present study reports a 56-year-old male with low-grade BilIN of the bile ducts and the cystic duct margin. Stent exchange endoscopy demonstrated an irregular, intraductal mass extending along the common bile duct, common hepatic duct, and hepatic duct bifurcation. The peribiliary mass was found to abut the right portal vein, inferior vena cava, and pancreatic head, and replaced the right hepatic artery. In addition, there was evidence of gallbladder adenoma managed with cholecystectomy and a right-lobed liver lesion and cirrhosis, which prompted the discussion of prophylactic liver transplantation. We emphasize the radiological features of BilIN and associated pathological findings through multiple imaging modalities. Consideration of this diagnosis is indicated in western countries and requires timely management based on available guidelines. |
format | Online Article Text |
id | pubmed-9449331 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-94493312022-09-13 Biliary Intraepithelial Neoplasia With Gallbladder Adenoma and Cirrhosis: A Case Report Chen, William J Wolff, Evan Varma, Chintalapati R Shoela, Ramy Cureus Radiology Biliary intraepithelial neoplasia (BilIN) is a precursor lesion of cholangiocarcinoma that has been rarely reported. The present study reports a 56-year-old male with low-grade BilIN of the bile ducts and the cystic duct margin. Stent exchange endoscopy demonstrated an irregular, intraductal mass extending along the common bile duct, common hepatic duct, and hepatic duct bifurcation. The peribiliary mass was found to abut the right portal vein, inferior vena cava, and pancreatic head, and replaced the right hepatic artery. In addition, there was evidence of gallbladder adenoma managed with cholecystectomy and a right-lobed liver lesion and cirrhosis, which prompted the discussion of prophylactic liver transplantation. We emphasize the radiological features of BilIN and associated pathological findings through multiple imaging modalities. Consideration of this diagnosis is indicated in western countries and requires timely management based on available guidelines. Cureus 2022-08-08 /pmc/articles/PMC9449331/ /pubmed/36106242 http://dx.doi.org/10.7759/cureus.27780 Text en Copyright © 2022, Chen et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Radiology Chen, William J Wolff, Evan Varma, Chintalapati R Shoela, Ramy Biliary Intraepithelial Neoplasia With Gallbladder Adenoma and Cirrhosis: A Case Report |
title | Biliary Intraepithelial Neoplasia With Gallbladder Adenoma and Cirrhosis: A Case Report |
title_full | Biliary Intraepithelial Neoplasia With Gallbladder Adenoma and Cirrhosis: A Case Report |
title_fullStr | Biliary Intraepithelial Neoplasia With Gallbladder Adenoma and Cirrhosis: A Case Report |
title_full_unstemmed | Biliary Intraepithelial Neoplasia With Gallbladder Adenoma and Cirrhosis: A Case Report |
title_short | Biliary Intraepithelial Neoplasia With Gallbladder Adenoma and Cirrhosis: A Case Report |
title_sort | biliary intraepithelial neoplasia with gallbladder adenoma and cirrhosis: a case report |
topic | Radiology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9449331/ https://www.ncbi.nlm.nih.gov/pubmed/36106242 http://dx.doi.org/10.7759/cureus.27780 |
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