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Gypenosides ameliorate high-fat diet-induced non-alcoholic steatohepatitis via farnesoid X receptor activation

BACKGROUND: Gypenosides (Gyps), the major botanical component of Gynostemma pentaphyllum, was found to up-regulate the farnesoid X receptor (FXR) in a mouse model of non-alcoholic steatohepatitis (NASH). However, the exact role of FXR and underlying mechanisms in Gyps-mediated effects on NASH remain...

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Detalles Bibliográficos
Autores principales:	Li, Hongshan, Xi, Yingfei, Liu, Hongliang, Xin, Xin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Nutrition
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9449333/ https://www.ncbi.nlm.nih.gov/pubmed/36091227 http://dx.doi.org/10.3389/fnut.2022.914079

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