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The molecular pathogenesis of triptolide-induced hepatotoxicity

Triptolide (TP) is the major pharmacologically active ingredient and toxic component of Tripterygium wilfordii Hook. f. However, its clinical potential is limited by a narrow therapeutic window and multiple organ toxicity, especially hepatotoxicity. Furthermore, TP-induced hepatotoxicity shows signi...

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Detalles Bibliográficos
Autores principales:	Hu, Yeqing, Wu, Qiguo, Wang, Yulin, Zhang, Haibo, Liu, Xueying, Zhou, Hua, Yang, Tao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9449346/ https://www.ncbi.nlm.nih.gov/pubmed/36091841 http://dx.doi.org/10.3389/fphar.2022.979307

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