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Immunological balance between Treg and Th17 lymphocytes as a key element of type 1 diabetes progression in children

Type 1 diabetes (T1D) is autoimmune destruction of the beta cells of pancreatic islets. Due to complexity of that disease, the mechanisms leading to the tolerance breakdown are still not fully understood. Previous hypothesis of imbalance in the Th1 and Th2 cells as the main contributing factor has b...

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Detalles Bibliográficos
Autores principales: Starosz, Aleksandra, Jamiołkowska-Sztabkowska, Milena, Głowińska-Olszewska, Barbara, Moniuszko, Marcin, Bossowski, Artur, Grubczak, Kamil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9449530/
https://www.ncbi.nlm.nih.gov/pubmed/36091019
http://dx.doi.org/10.3389/fimmu.2022.958430