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Infusion of C20:0 ceramide into ventral hippocampus triggers anhedonia-like behavior in female and male rats
Increased long-chain C20:0 ceramides have been found in the serum of patients with depression. Moreover, ceramides are linked with increased microglia reactivity and inflammatory cytokine production, which are associated with depression. Since ceramides can readily cross the blood brain barrier, per...
Autores principales: | Sambolín-Escobales, Lubriel, Feliciano-Quiñones, Adariana, Tirado-Castro, Lizmarie, Suárez, Cristina, Pacheco-Cruz, Dariangelly, Irizarry-Méndez, Nashaly, Fonseca-Ferrer, Wilfred, Hernández-López, Anixa, Colón-Romero, María, Porter, James T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9449580/ https://www.ncbi.nlm.nih.gov/pubmed/36090653 http://dx.doi.org/10.3389/fnbeh.2022.899627 |
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