Asystole-induced Bradycardia by Dexmedetomidine during Endoscopic Submucosal Dissection

Although dexmedetomidine (DEX) is a widely used analgesic and sedative agent for endoscopic procedures, cardiovascular complications, such as bradycardia and hypotension, are frequently experienced. We herein report the first case of asystole-induced bradycardia due to DEX during endoscopic submucos...

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Autores principales: Yamasaki, Tomoaki, Sakata, Yuhei, Suekane, Takehisa, Nebiki, Hiroko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9449608/
https://www.ncbi.nlm.nih.gov/pubmed/35110487
http://dx.doi.org/10.2169/internalmedicine.8813-21
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author Yamasaki, Tomoaki
Sakata, Yuhei
Suekane, Takehisa
Nebiki, Hiroko
author_facet Yamasaki, Tomoaki
Sakata, Yuhei
Suekane, Takehisa
Nebiki, Hiroko
author_sort Yamasaki, Tomoaki
collection PubMed
description Although dexmedetomidine (DEX) is a widely used analgesic and sedative agent for endoscopic procedures, cardiovascular complications, such as bradycardia and hypotension, are frequently experienced. We herein report the first case of asystole-induced bradycardia due to DEX during endoscopic submucosal dissection (ESD). An 81-year-old man without cardiovascular diseases was referred for gastric carcinoma. ESD was started after administering a loading dose of DEX followed by a continuous maintenance infusion of DEX. The patient's heart rate gradually decreased, and then cardiac arrest occurred. DEX has a risk of cardiac arrest, so bradycardia should not be underestimated during sedation with DEX.
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spelling pubmed-94496082022-09-19 Asystole-induced Bradycardia by Dexmedetomidine during Endoscopic Submucosal Dissection Yamasaki, Tomoaki Sakata, Yuhei Suekane, Takehisa Nebiki, Hiroko Intern Med Case Report Although dexmedetomidine (DEX) is a widely used analgesic and sedative agent for endoscopic procedures, cardiovascular complications, such as bradycardia and hypotension, are frequently experienced. We herein report the first case of asystole-induced bradycardia due to DEX during endoscopic submucosal dissection (ESD). An 81-year-old man without cardiovascular diseases was referred for gastric carcinoma. ESD was started after administering a loading dose of DEX followed by a continuous maintenance infusion of DEX. The patient's heart rate gradually decreased, and then cardiac arrest occurred. DEX has a risk of cardiac arrest, so bradycardia should not be underestimated during sedation with DEX. The Japanese Society of Internal Medicine 2022-02-01 2022-08-15 /pmc/articles/PMC9449608/ /pubmed/35110487 http://dx.doi.org/10.2169/internalmedicine.8813-21 Text en Copyright © 2022 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Yamasaki, Tomoaki
Sakata, Yuhei
Suekane, Takehisa
Nebiki, Hiroko
Asystole-induced Bradycardia by Dexmedetomidine during Endoscopic Submucosal Dissection
title Asystole-induced Bradycardia by Dexmedetomidine during Endoscopic Submucosal Dissection
title_full Asystole-induced Bradycardia by Dexmedetomidine during Endoscopic Submucosal Dissection
title_fullStr Asystole-induced Bradycardia by Dexmedetomidine during Endoscopic Submucosal Dissection
title_full_unstemmed Asystole-induced Bradycardia by Dexmedetomidine during Endoscopic Submucosal Dissection
title_short Asystole-induced Bradycardia by Dexmedetomidine during Endoscopic Submucosal Dissection
title_sort asystole-induced bradycardia by dexmedetomidine during endoscopic submucosal dissection
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9449608/
https://www.ncbi.nlm.nih.gov/pubmed/35110487
http://dx.doi.org/10.2169/internalmedicine.8813-21
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