Severe Gastrointestinal Disorder Due to Capecitabine Associated with Dihydropyrimidine Dehydrogenase Deficiency: A Case Report and Literature Review

Dihydropyrimidine dehydrogenase (DPD) deficiency induces severe adverse events in patients receiving fluoropyrimidines. We encountered a 64-year-old DPD-deficient man with a severe capecitabine-related gastrointestinal disorder. He received capecitabine-containing chemotherapy after rectal cancer re...

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Detalles Bibliográficos
Autores principales: Hagiwara, Yuya, Yamamoto, Yoshiyuki, Inagaki, Yuki, Tomisaki, Reina, Tsuji, Miki, Fukuda, Soma, Fukuda, Satoshi, Onoda, Tsubasa, Suzuki, Hirosumi, Niisato, Yusuke, Tange, Yoshitaka, Ikeda, Naoya, Yamada, Keiichi, Kobayashi, Mariko, Akutsu, Daisuke, Yamada, Takeshi, Moriwaki, Toshikazu, Narasaka, Toshiaki, Suzuki, Hideo, Tsuchiya, Kiichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9449621/
https://www.ncbi.nlm.nih.gov/pubmed/35110482
http://dx.doi.org/10.2169/internalmedicine.8636-21

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