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Synergistic targeting of the PI3K/mTOR and MAPK/ERK pathways in Merkel cell carcinoma

Merkel cell carcinoma (MCC) is an aggressive type of skin cancer, which is caused either by integration of the oncogenic Merkel cell polyomavirus (MCPyV) or by accumulation of UV-light induced mutations. Since the response to immune-checkpoint inhibitors is limited, new therapeutic agents need to be...

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Detalles Bibliográficos
Autores principales:	Temblador, Arturo, Topalis, Dimitrios, Andrei, Graciela, Snoeck, Robert
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Full Length Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9449649/ https://www.ncbi.nlm.nih.gov/pubmed/36007768 http://dx.doi.org/10.1016/j.tvr.2022.200244

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