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Application of MXene in the diagnosis and treatment of breast cancer: A critical overview

Breast cancer is the second most common cancer worldwide. Prognosis and timely treatment can reduce the illness or improve it. The use of nanomaterials leads to timely diagnosis and effective treatment. MXenes are a 2D material with a unique composition of attributes, containing significant electric...

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Autores principales: Ranjbari, Sara, Darroudi, Mahdieh, Hatamluyi, Behnaz, Arefinia, Reza, Aghaee-Bakhtiari, Seyed Hamid, Rezayi, Majid, Khazaei, Majid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9449700/
https://www.ncbi.nlm.nih.gov/pubmed/36091438
http://dx.doi.org/10.3389/fbioe.2022.984336
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author Ranjbari, Sara
Darroudi, Mahdieh
Hatamluyi, Behnaz
Arefinia, Reza
Aghaee-Bakhtiari, Seyed Hamid
Rezayi, Majid
Khazaei, Majid
author_facet Ranjbari, Sara
Darroudi, Mahdieh
Hatamluyi, Behnaz
Arefinia, Reza
Aghaee-Bakhtiari, Seyed Hamid
Rezayi, Majid
Khazaei, Majid
author_sort Ranjbari, Sara
collection PubMed
description Breast cancer is the second most common cancer worldwide. Prognosis and timely treatment can reduce the illness or improve it. The use of nanomaterials leads to timely diagnosis and effective treatment. MXenes are a 2D material with a unique composition of attributes, containing significant electrical conductance, high optical characteristics, mechanical consistency, and excellent optical properties. Current advances and insights show that MXene is far more promising in biotechnology applications than current nanobiotechnology systems. MXenes have various applications in biotechnology and biomedicine, such as drug delivery/loading, biosensor, cancer treatment, and bioimaging programs due to their high surface area, excellent biocompatibility, and physicochemical properties. Surface modifications MXenes are not only biocompatible but also have multifunctional properties, such as aiming ligands for preferential agglomeration at the tumor sites for photothermal treatment. Studies have shown that these nanostructures, detection, and breast cancer therapy are more acceptable than present nanosystems in in vivo and in vitro. This review article aims to investigate the structure of MXene, its various synthesis methods, its application to cancer diagnosis, cytotoxicity, biodegradability, and cancer treatment by the photothermal process (in-vivo and in-vitro).
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spelling pubmed-94497002022-09-08 Application of MXene in the diagnosis and treatment of breast cancer: A critical overview Ranjbari, Sara Darroudi, Mahdieh Hatamluyi, Behnaz Arefinia, Reza Aghaee-Bakhtiari, Seyed Hamid Rezayi, Majid Khazaei, Majid Front Bioeng Biotechnol Bioengineering and Biotechnology Breast cancer is the second most common cancer worldwide. Prognosis and timely treatment can reduce the illness or improve it. The use of nanomaterials leads to timely diagnosis and effective treatment. MXenes are a 2D material with a unique composition of attributes, containing significant electrical conductance, high optical characteristics, mechanical consistency, and excellent optical properties. Current advances and insights show that MXene is far more promising in biotechnology applications than current nanobiotechnology systems. MXenes have various applications in biotechnology and biomedicine, such as drug delivery/loading, biosensor, cancer treatment, and bioimaging programs due to their high surface area, excellent biocompatibility, and physicochemical properties. Surface modifications MXenes are not only biocompatible but also have multifunctional properties, such as aiming ligands for preferential agglomeration at the tumor sites for photothermal treatment. Studies have shown that these nanostructures, detection, and breast cancer therapy are more acceptable than present nanosystems in in vivo and in vitro. This review article aims to investigate the structure of MXene, its various synthesis methods, its application to cancer diagnosis, cytotoxicity, biodegradability, and cancer treatment by the photothermal process (in-vivo and in-vitro). Frontiers Media S.A. 2022-08-24 /pmc/articles/PMC9449700/ /pubmed/36091438 http://dx.doi.org/10.3389/fbioe.2022.984336 Text en Copyright © 2022 Ranjbari, Darroudi, Hatamluyi, Arefinia, Aghaee-Bakhtiari, Rezayi and Khazaei. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Bioengineering and Biotechnology
Ranjbari, Sara
Darroudi, Mahdieh
Hatamluyi, Behnaz
Arefinia, Reza
Aghaee-Bakhtiari, Seyed Hamid
Rezayi, Majid
Khazaei, Majid
Application of MXene in the diagnosis and treatment of breast cancer: A critical overview
title Application of MXene in the diagnosis and treatment of breast cancer: A critical overview
title_full Application of MXene in the diagnosis and treatment of breast cancer: A critical overview
title_fullStr Application of MXene in the diagnosis and treatment of breast cancer: A critical overview
title_full_unstemmed Application of MXene in the diagnosis and treatment of breast cancer: A critical overview
title_short Application of MXene in the diagnosis and treatment of breast cancer: A critical overview
title_sort application of mxene in the diagnosis and treatment of breast cancer: a critical overview
topic Bioengineering and Biotechnology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9449700/
https://www.ncbi.nlm.nih.gov/pubmed/36091438
http://dx.doi.org/10.3389/fbioe.2022.984336
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