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Evaluating the therapeutic efficacy of triptolide and (S)-10-hydroxycamptothecin on cutaneous and ocular Herpes Simplex Virus type-1 infections in mice
OBJECTIVE: The emergence of Acyclovir-Resistant Herpes Simplex Virus type-1, which is the result of clinical over usage calls for the urgent need of a novel anti-HSV agent. Hence, the activity of Triptolide (TP) and (S)-10-Hydroxycamptothecin (10-HCPT) were investigated as natural products in two in...
Autores principales: | Aliabadi, Nasrin, Jamalidoust, Marzieh, Pouladfar, Gholamreza, Azarpira, Negar, Ziyaeyan, Atoosa, Ziyaeyan, Mazyar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9449773/ https://www.ncbi.nlm.nih.gov/pubmed/36090228 http://dx.doi.org/10.1016/j.heliyon.2022.e10348 |
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