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Evaluating the therapeutic efficacy of triptolide and (S)-10-hydroxycamptothecin on cutaneous and ocular Herpes Simplex Virus type-1 infections in mice

OBJECTIVE: The emergence of Acyclovir-Resistant Herpes Simplex Virus type-1, which is the result of clinical over usage calls for the urgent need of a novel anti-HSV agent. Hence, the activity of Triptolide (TP) and (S)-10-Hydroxycamptothecin (10-HCPT) were investigated as natural products in two in...

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Detalles Bibliográficos
Autores principales: Aliabadi, Nasrin, Jamalidoust, Marzieh, Pouladfar, Gholamreza, Azarpira, Negar, Ziyaeyan, Atoosa, Ziyaeyan, Mazyar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9449773/
https://www.ncbi.nlm.nih.gov/pubmed/36090228
http://dx.doi.org/10.1016/j.heliyon.2022.e10348

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