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Gonadal bacterial community composition is associated with sex-specific differences in swamp eels (Monopterus albus)
Organisms are colonized by microorganism communities and play a pivotal role in host function by influencing physiology and development. In mammals, bacterial community may alter gonadal maturation and drive sex-specific differences in gene expression and metabolism. However, bacterial microbiota di...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9449807/ https://www.ncbi.nlm.nih.gov/pubmed/36091072 http://dx.doi.org/10.3389/fimmu.2022.938326 |
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author | Meng, Kaifeng Lin, Xing Liu, Hairong Chen, Huijie Liu, Fei Xu, Zhen Sun, Yonghua Luo, Daji |
author_facet | Meng, Kaifeng Lin, Xing Liu, Hairong Chen, Huijie Liu, Fei Xu, Zhen Sun, Yonghua Luo, Daji |
author_sort | Meng, Kaifeng |
collection | PubMed |
description | Organisms are colonized by microorganism communities and play a pivotal role in host function by influencing physiology and development. In mammals, bacterial community may alter gonadal maturation and drive sex-specific differences in gene expression and metabolism. However, bacterial microbiota diversity in the gonads of early vertebrates has not been fully elucidated. Here, we focused on the swamp eel (Monopterus albus), which naturally undergoes sex reversal, and systematically analyzed the bacterial microbiota profiles between females and males using 16S rRNA gene sequences. Specifically, the microbial abundance and community diversity of gonads in males were higher than in females. Although Proteobacteria, Firmicutes, Bacteroidetes, and Actinobacteria were characterized as the dominating phyla in ovary and testis, the relative abundance of Firmicutes was significantly higher in males than females. Detailed analysis of the microbial community revealed that Bacilli were the dominant bacteria in ovaries and Clostridium in testes of M. albus. More importantly, we proposed that differences in the microbial composition and distribution between ovaries and testes may be linked to functional categories in M. albus, especially metabolism. These findings represent a unique resource of bacterial community in gonads to facilitate future research about the mechanism of how microbiota influence sex-specific differences and sex reversal in vertebrates. |
format | Online Article Text |
id | pubmed-9449807 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-94498072022-09-08 Gonadal bacterial community composition is associated with sex-specific differences in swamp eels (Monopterus albus) Meng, Kaifeng Lin, Xing Liu, Hairong Chen, Huijie Liu, Fei Xu, Zhen Sun, Yonghua Luo, Daji Front Immunol Immunology Organisms are colonized by microorganism communities and play a pivotal role in host function by influencing physiology and development. In mammals, bacterial community may alter gonadal maturation and drive sex-specific differences in gene expression and metabolism. However, bacterial microbiota diversity in the gonads of early vertebrates has not been fully elucidated. Here, we focused on the swamp eel (Monopterus albus), which naturally undergoes sex reversal, and systematically analyzed the bacterial microbiota profiles between females and males using 16S rRNA gene sequences. Specifically, the microbial abundance and community diversity of gonads in males were higher than in females. Although Proteobacteria, Firmicutes, Bacteroidetes, and Actinobacteria were characterized as the dominating phyla in ovary and testis, the relative abundance of Firmicutes was significantly higher in males than females. Detailed analysis of the microbial community revealed that Bacilli were the dominant bacteria in ovaries and Clostridium in testes of M. albus. More importantly, we proposed that differences in the microbial composition and distribution between ovaries and testes may be linked to functional categories in M. albus, especially metabolism. These findings represent a unique resource of bacterial community in gonads to facilitate future research about the mechanism of how microbiota influence sex-specific differences and sex reversal in vertebrates. Frontiers Media S.A. 2022-08-24 /pmc/articles/PMC9449807/ /pubmed/36091072 http://dx.doi.org/10.3389/fimmu.2022.938326 Text en Copyright © 2022 Meng, Lin, Liu, Chen, Liu, Xu, Sun and Luo https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Immunology Meng, Kaifeng Lin, Xing Liu, Hairong Chen, Huijie Liu, Fei Xu, Zhen Sun, Yonghua Luo, Daji Gonadal bacterial community composition is associated with sex-specific differences in swamp eels (Monopterus albus) |
title | Gonadal bacterial community composition is associated with sex-specific differences in swamp eels (Monopterus albus)
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title_full | Gonadal bacterial community composition is associated with sex-specific differences in swamp eels (Monopterus albus)
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title_fullStr | Gonadal bacterial community composition is associated with sex-specific differences in swamp eels (Monopterus albus)
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title_full_unstemmed | Gonadal bacterial community composition is associated with sex-specific differences in swamp eels (Monopterus albus)
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title_short | Gonadal bacterial community composition is associated with sex-specific differences in swamp eels (Monopterus albus)
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title_sort | gonadal bacterial community composition is associated with sex-specific differences in swamp eels (monopterus albus) |
topic | Immunology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9449807/ https://www.ncbi.nlm.nih.gov/pubmed/36091072 http://dx.doi.org/10.3389/fimmu.2022.938326 |
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