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Lack of VMP1 impairs hepatic lipoprotein secretion and promotes non-alcoholic steatohepatitis

BACKGROUND & AIMS: Vacuole membrane protein 1 (VMP1) is an endoplasmic reticulum (ER) transmembrane protein that regulates the formation of autophagosomes and lipid droplets. Recent evidence suggests that VMP1 plays a critical role in lipoprotein secretion in zebra fish and cultured cells. Howev...

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Detalles Bibliográficos
Autores principales:	Jiang, Xiaoxiao, Fulte, Sam, Deng, Fengyan, Chen, Shiyuan, Xie, Yan, Chao, Xiaojuan, He, Xi C., Zhang, Yuxia, Li, Tiangang, Li, Feng, McCoin, Colin, Morris, E. Matthew, Thyfault, John, Liu, Wanqing, Li, Linheng, Davidson, Nicholas O., Ding, Wen-Xing, Ni, Hong-Min
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9449865/ https://www.ncbi.nlm.nih.gov/pubmed/35452693 http://dx.doi.org/10.1016/j.jhep.2022.04.010

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