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Digital psychosocial intervention for depression among older adults in socioeconomically deprived areas in Brazil (PRODIGITAL-D): protocol for an individually randomised controlled trial

BACKGROUND: Depression in older adults is a challenge for health systems in most low- and middle-income countries (LMICs). Digital strategies for the management of this condition have been emerging worldwide, but the effectiveness of most of them is still unclear, especially among older adults. Thus...

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Autores principales: Nakamura, Carina Akemi, Scazufca, Marcia, Moretti, Felipe Azevedo, Didone, Thiago Vinicius Nadaleto, de Sá Martins, Mariana Mendes, Pereira, Luara Aragoni, de Souza, Caio Hudson Queiroz, de Oliveira, Gabriel Macias, da Costa, Marcelo Oliveira, Machado, Marcelo, da Silva Bitencourt, Evelyn, dos Santos, Monica Souza, Murdoch, Jamie, van de Ven, Pepijn, Seward, Nadine, Hollingworth, William, Peters, Tim J., Araya, Ricardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9449935/
https://www.ncbi.nlm.nih.gov/pubmed/36071463
http://dx.doi.org/10.1186/s13063-022-06623-z
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author Nakamura, Carina Akemi
Scazufca, Marcia
Moretti, Felipe Azevedo
Didone, Thiago Vinicius Nadaleto
de Sá Martins, Mariana Mendes
Pereira, Luara Aragoni
de Souza, Caio Hudson Queiroz
de Oliveira, Gabriel Macias
da Costa, Marcelo Oliveira
Machado, Marcelo
da Silva Bitencourt, Evelyn
dos Santos, Monica Souza
Murdoch, Jamie
van de Ven, Pepijn
Seward, Nadine
Hollingworth, William
Peters, Tim J.
Araya, Ricardo
author_facet Nakamura, Carina Akemi
Scazufca, Marcia
Moretti, Felipe Azevedo
Didone, Thiago Vinicius Nadaleto
de Sá Martins, Mariana Mendes
Pereira, Luara Aragoni
de Souza, Caio Hudson Queiroz
de Oliveira, Gabriel Macias
da Costa, Marcelo Oliveira
Machado, Marcelo
da Silva Bitencourt, Evelyn
dos Santos, Monica Souza
Murdoch, Jamie
van de Ven, Pepijn
Seward, Nadine
Hollingworth, William
Peters, Tim J.
Araya, Ricardo
author_sort Nakamura, Carina Akemi
collection PubMed
description BACKGROUND: Depression in older adults is a challenge for health systems in most low- and middle-income countries (LMICs). Digital strategies for the management of this condition have been emerging worldwide, but the effectiveness of most of them is still unclear, especially among older adults. Thus, we aim to assess the effectiveness and cost-effectiveness of a digital psychosocial intervention to treat depression among older adults living in socioeconomically deprived areas in Guarulhos, Brazil. METHODS: We will conduct a two-arm individually randomised controlled trial with 1:1 allocation ratio. Five hundred older adults aged 60 years or over with depressive symptomatology (9-item Patient Health Questionnaire score, PHQ-9 ≥ 10) and registered with one of the primary care clinics will be recruited to participate in this study. A 6-week digital psychosocial programme, named Viva Vida, will be delivered via WhatsApp to participants allocated to the intervention arm. The Viva Vida will send psychoeducational and behavioural activation audio and visual messages 4 days a week for 6 weeks. The control arm will only receive a single message with general information about depression. The primary outcome will be the proportion of depression recovery (PHQ-9 < 10) assessed at 3 months. The cost-effectiveness of the intervention will be assessed at 5 months. A detailed process evaluation will be used to explore context and important implementation outcomes. DISCUSSION: This programme was based on the PROACTIVE intervention and designed to be delivered without face-to-face contact. If effective, it could be a simple treatment option, appropriate not only when social distancing is required, but it could also be included as a regular public health programme to initiate depression treatment, particularly in LMICs where resources allocated to mental health are scarce. TRIAL REGISTRATION: Registro Brasileiro de Ensaios Clínicos (ReBEC), RBR-4c94dtn. Registered on 22 October 2021 (submitted on 03 August 2021).
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spelling pubmed-94499352022-09-07 Digital psychosocial intervention for depression among older adults in socioeconomically deprived areas in Brazil (PRODIGITAL-D): protocol for an individually randomised controlled trial Nakamura, Carina Akemi Scazufca, Marcia Moretti, Felipe Azevedo Didone, Thiago Vinicius Nadaleto de Sá Martins, Mariana Mendes Pereira, Luara Aragoni de Souza, Caio Hudson Queiroz de Oliveira, Gabriel Macias da Costa, Marcelo Oliveira Machado, Marcelo da Silva Bitencourt, Evelyn dos Santos, Monica Souza Murdoch, Jamie van de Ven, Pepijn Seward, Nadine Hollingworth, William Peters, Tim J. Araya, Ricardo Trials Study Protocol BACKGROUND: Depression in older adults is a challenge for health systems in most low- and middle-income countries (LMICs). Digital strategies for the management of this condition have been emerging worldwide, but the effectiveness of most of them is still unclear, especially among older adults. Thus, we aim to assess the effectiveness and cost-effectiveness of a digital psychosocial intervention to treat depression among older adults living in socioeconomically deprived areas in Guarulhos, Brazil. METHODS: We will conduct a two-arm individually randomised controlled trial with 1:1 allocation ratio. Five hundred older adults aged 60 years or over with depressive symptomatology (9-item Patient Health Questionnaire score, PHQ-9 ≥ 10) and registered with one of the primary care clinics will be recruited to participate in this study. A 6-week digital psychosocial programme, named Viva Vida, will be delivered via WhatsApp to participants allocated to the intervention arm. The Viva Vida will send psychoeducational and behavioural activation audio and visual messages 4 days a week for 6 weeks. The control arm will only receive a single message with general information about depression. The primary outcome will be the proportion of depression recovery (PHQ-9 < 10) assessed at 3 months. The cost-effectiveness of the intervention will be assessed at 5 months. A detailed process evaluation will be used to explore context and important implementation outcomes. DISCUSSION: This programme was based on the PROACTIVE intervention and designed to be delivered without face-to-face contact. If effective, it could be a simple treatment option, appropriate not only when social distancing is required, but it could also be included as a regular public health programme to initiate depression treatment, particularly in LMICs where resources allocated to mental health are scarce. TRIAL REGISTRATION: Registro Brasileiro de Ensaios Clínicos (ReBEC), RBR-4c94dtn. Registered on 22 October 2021 (submitted on 03 August 2021). BioMed Central 2022-09-07 /pmc/articles/PMC9449935/ /pubmed/36071463 http://dx.doi.org/10.1186/s13063-022-06623-z Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Study Protocol
Nakamura, Carina Akemi
Scazufca, Marcia
Moretti, Felipe Azevedo
Didone, Thiago Vinicius Nadaleto
de Sá Martins, Mariana Mendes
Pereira, Luara Aragoni
de Souza, Caio Hudson Queiroz
de Oliveira, Gabriel Macias
da Costa, Marcelo Oliveira
Machado, Marcelo
da Silva Bitencourt, Evelyn
dos Santos, Monica Souza
Murdoch, Jamie
van de Ven, Pepijn
Seward, Nadine
Hollingworth, William
Peters, Tim J.
Araya, Ricardo
Digital psychosocial intervention for depression among older adults in socioeconomically deprived areas in Brazil (PRODIGITAL-D): protocol for an individually randomised controlled trial
title Digital psychosocial intervention for depression among older adults in socioeconomically deprived areas in Brazil (PRODIGITAL-D): protocol for an individually randomised controlled trial
title_full Digital psychosocial intervention for depression among older adults in socioeconomically deprived areas in Brazil (PRODIGITAL-D): protocol for an individually randomised controlled trial
title_fullStr Digital psychosocial intervention for depression among older adults in socioeconomically deprived areas in Brazil (PRODIGITAL-D): protocol for an individually randomised controlled trial
title_full_unstemmed Digital psychosocial intervention for depression among older adults in socioeconomically deprived areas in Brazil (PRODIGITAL-D): protocol for an individually randomised controlled trial
title_short Digital psychosocial intervention for depression among older adults in socioeconomically deprived areas in Brazil (PRODIGITAL-D): protocol for an individually randomised controlled trial
title_sort digital psychosocial intervention for depression among older adults in socioeconomically deprived areas in brazil (prodigital-d): protocol for an individually randomised controlled trial
topic Study Protocol
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9449935/
https://www.ncbi.nlm.nih.gov/pubmed/36071463
http://dx.doi.org/10.1186/s13063-022-06623-z
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