The deficiency in Th2-like Tfh cells affects the maturation and quality of HIV-specific B cell response in viremic infection

Optimal T follicular helper (Tfh) cells function is important to promote the development of germinal centers and maturation of high affinity antigen-specific B cells. We have found that the expression of CXCR3 defines distinct Tfh subsets: CXCR3(+) Th1-like Tfh cells mainly producing single IFN-γ an...

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Detalles Bibliográficos
Autores principales: Noto, Alessandra, Suffiotti, Madeleine, Joo, Victor, Mancarella, Antonio, Procopio, Francesco A., Cavet, Guy, Leung, Yvonne, Corpataux, Jean-Marc, Cavassini, Matthias, Riva, Agostino, Stamatatos, Leonidas, Gottardo, Raphael, McDermott, Adrian B., Koup, Richard A., Fenwick, Craig, Perreau, Matthieu, Pantaleo, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9450063/
https://www.ncbi.nlm.nih.gov/pubmed/36091040
http://dx.doi.org/10.3389/fimmu.2022.960120

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