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Degradation kinetics of artesunate for the development of an ex-tempore intravenous injection

BACKGROUND: Artesunate is recommended by the World Health Organization (WHO) for parenteral treatment of severe Plasmodium falciparum malaria. However, artesunate is inherently unstable in an aqueous solution and hydrolyses rapidly after its preparation for injection. Therefore, the aim of the study...

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Detalles Bibliográficos
Autores principales:	Gashe, Fanta, Wynendaele, Evelien, De Spiegeleer, Bart, Suleman, Sultan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9450271/ https://www.ncbi.nlm.nih.gov/pubmed/36068561 http://dx.doi.org/10.1186/s12936-022-04278-4

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