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Comparison and impact of associated anomalies on the anal position index in neonates with anorectal malformation

OBJECTIVE: Some prognostic factors have affected the functional outcomes of patients with anorectal malformations (ARM) after definitive surgery, including the associated anomalies. Moreover, the anal position index (API) study in neonates from developing countries is minimal. We aimed to (1) compar...

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Autores principales: Pitaka, Ririd Tri, Fauzi, Aditya Rifqi, Makhmudi, Akhmad, Gunadi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9450298/
https://www.ncbi.nlm.nih.gov/pubmed/36071457
http://dx.doi.org/10.1186/s13104-022-06186-x
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author Pitaka, Ririd Tri
Fauzi, Aditya Rifqi
Makhmudi, Akhmad
Gunadi
author_facet Pitaka, Ririd Tri
Fauzi, Aditya Rifqi
Makhmudi, Akhmad
Gunadi
author_sort Pitaka, Ririd Tri
collection PubMed
description OBJECTIVE: Some prognostic factors have affected the functional outcomes of patients with anorectal malformations (ARM) after definitive surgery, including the associated anomalies. Moreover, the anal position index (API) study in neonates from developing countries is minimal. We aimed to (1) compare the API between neonates with ARM and controls; and (2) determine the impact of associated anomalies on the API in neonates with ARM. RESULTS: We ascertained 68 subjects: 35 neonates with ARM and 33 controls. The API of neonates with ARM was similar to controls, either male or female neonates (p = 0.51 and 0.90, respectively). Interestingly, the API in ARM males with associated anomalies (0.42 ± 0.07) was significantly lower than in control males (0.48 ± 0.02) (p = 0.005). Moreover, the API of ARM neonates with vertebral anomalies (0.35 ± 0.04) was lower than ARM neonates without vertebral anomalies (0.47 ± 0.07) (p = 0.021). In conclusion, associated anomalies and sex might affect the API in neonates with ARM. These findings should be considered and informed during counseling to the parents regarding the prognosis of functional outcomes in ARM neonates, particularly with associated anomalies. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s13104-022-06186-x.
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spelling pubmed-94502982022-09-08 Comparison and impact of associated anomalies on the anal position index in neonates with anorectal malformation Pitaka, Ririd Tri Fauzi, Aditya Rifqi Makhmudi, Akhmad Gunadi BMC Res Notes Research Note OBJECTIVE: Some prognostic factors have affected the functional outcomes of patients with anorectal malformations (ARM) after definitive surgery, including the associated anomalies. Moreover, the anal position index (API) study in neonates from developing countries is minimal. We aimed to (1) compare the API between neonates with ARM and controls; and (2) determine the impact of associated anomalies on the API in neonates with ARM. RESULTS: We ascertained 68 subjects: 35 neonates with ARM and 33 controls. The API of neonates with ARM was similar to controls, either male or female neonates (p = 0.51 and 0.90, respectively). Interestingly, the API in ARM males with associated anomalies (0.42 ± 0.07) was significantly lower than in control males (0.48 ± 0.02) (p = 0.005). Moreover, the API of ARM neonates with vertebral anomalies (0.35 ± 0.04) was lower than ARM neonates without vertebral anomalies (0.47 ± 0.07) (p = 0.021). In conclusion, associated anomalies and sex might affect the API in neonates with ARM. These findings should be considered and informed during counseling to the parents regarding the prognosis of functional outcomes in ARM neonates, particularly with associated anomalies. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s13104-022-06186-x. BioMed Central 2022-09-07 /pmc/articles/PMC9450298/ /pubmed/36071457 http://dx.doi.org/10.1186/s13104-022-06186-x Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research Note
Pitaka, Ririd Tri
Fauzi, Aditya Rifqi
Makhmudi, Akhmad
Gunadi
Comparison and impact of associated anomalies on the anal position index in neonates with anorectal malformation
title Comparison and impact of associated anomalies on the anal position index in neonates with anorectal malformation
title_full Comparison and impact of associated anomalies on the anal position index in neonates with anorectal malformation
title_fullStr Comparison and impact of associated anomalies on the anal position index in neonates with anorectal malformation
title_full_unstemmed Comparison and impact of associated anomalies on the anal position index in neonates with anorectal malformation
title_short Comparison and impact of associated anomalies on the anal position index in neonates with anorectal malformation
title_sort comparison and impact of associated anomalies on the anal position index in neonates with anorectal malformation
topic Research Note
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9450298/
https://www.ncbi.nlm.nih.gov/pubmed/36071457
http://dx.doi.org/10.1186/s13104-022-06186-x
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