ASXL1/2 mutations and myeloid malignancies

Myeloid malignancies develop through the accumulation of genetic and epigenetic alterations that dysregulate hematopoietic stem cell (HSC) self-renewal, stimulate HSC proliferation and result in differentiation defects. The polycomb group (PcG) and trithorax group (TrxG) of epigenetic regulators act...

Descripción completa

Detalles Bibliográficos
Autores principales: Medina, Edward A., Delma, Caroline R., Yang, Feng-Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9450349/
https://www.ncbi.nlm.nih.gov/pubmed/36068610
http://dx.doi.org/10.1186/s13045-022-01336-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9450349/
https://www.ncbi.nlm.nih.gov/pubmed/36068610
http://dx.doi.org/10.1186/s13045-022-01336-x

Ejemplares similares