Abnormal molecular signatures of inflammation, energy metabolism, and vesicle biology in human Huntington disease peripheral tissues

BACKGROUND: A major challenge in neurodegenerative diseases concerns identifying biological disease signatures that track with disease progression or respond to an intervention. Several clinical trials in Huntington disease (HD), an inherited, progressive neurodegenerative disease, are currently ong...

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Detalles Bibliográficos
Autores principales: Neueder, Andreas, Kojer, Kerstin, Hering, Tanja, Lavery, Daniel J., Chen, Jian, Birth, Nathalie, Hallitsch, Jaqueline, Trautmann, Sonja, Parker, Jennifer, Flower, Michael, Sethi, Huma, Haider, Salman, Lee, Jong-Min, Tabrizi, Sarah J., Orth, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9450392/
https://www.ncbi.nlm.nih.gov/pubmed/36071529
http://dx.doi.org/10.1186/s13059-022-02752-5

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