COVID-19 in patients with B cell immune deficiency

This article aims to describe the clinical manifestations and management of COVID-19 in patients with primary and secondary B cell deficient states. We describe the epidemiologic and clinical features as well as unique management paradigm including isolation precautions with COVID-19. We then focus...

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Detalles Bibliográficos
Autores principales: Vergidis, Paschalis, Levy, Emily R., Ristagno, Elizabeth H., Iyer, Vivek N., O'Horo, John C., Joshi, Avni Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9450485/
https://www.ncbi.nlm.nih.gov/pubmed/36087764
http://dx.doi.org/10.1016/j.jim.2022.113351
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author Vergidis, Paschalis
Levy, Emily R.
Ristagno, Elizabeth H.
Iyer, Vivek N.
O'Horo, John C.
Joshi, Avni Y.
author_facet Vergidis, Paschalis
Levy, Emily R.
Ristagno, Elizabeth H.
Iyer, Vivek N.
O'Horo, John C.
Joshi, Avni Y.
author_sort Vergidis, Paschalis
collection PubMed
description This article aims to describe the clinical manifestations and management of COVID-19 in patients with primary and secondary B cell deficient states. We describe the epidemiologic and clinical features as well as unique management paradigm including isolation precautions with COVID-19. We then focus upon primary and secondary preventive approaches including vaccination and pre- as well as post-exposure prophylaxis. Further, we elaborate upon the important disease specific risk factors in these patients and the need to conduct prospective clinical trials to develop individualized management strategies in this population.
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spelling pubmed-94504852022-09-07 COVID-19 in patients with B cell immune deficiency Vergidis, Paschalis Levy, Emily R. Ristagno, Elizabeth H. Iyer, Vivek N. O'Horo, John C. Joshi, Avni Y. J Immunol Methods Article This article aims to describe the clinical manifestations and management of COVID-19 in patients with primary and secondary B cell deficient states. We describe the epidemiologic and clinical features as well as unique management paradigm including isolation precautions with COVID-19. We then focus upon primary and secondary preventive approaches including vaccination and pre- as well as post-exposure prophylaxis. Further, we elaborate upon the important disease specific risk factors in these patients and the need to conduct prospective clinical trials to develop individualized management strategies in this population. Elsevier B.V. 2022-11 2022-09-07 /pmc/articles/PMC9450485/ /pubmed/36087764 http://dx.doi.org/10.1016/j.jim.2022.113351 Text en © 2022 Elsevier B.V. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Vergidis, Paschalis
Levy, Emily R.
Ristagno, Elizabeth H.
Iyer, Vivek N.
O'Horo, John C.
Joshi, Avni Y.
COVID-19 in patients with B cell immune deficiency
title COVID-19 in patients with B cell immune deficiency
title_full COVID-19 in patients with B cell immune deficiency
title_fullStr COVID-19 in patients with B cell immune deficiency
title_full_unstemmed COVID-19 in patients with B cell immune deficiency
title_short COVID-19 in patients with B cell immune deficiency
title_sort covid-19 in patients with b cell immune deficiency
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9450485/
https://www.ncbi.nlm.nih.gov/pubmed/36087764
http://dx.doi.org/10.1016/j.jim.2022.113351
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