Age-related decline in the resistance of mice to bacterial infection and in LPS/TLR4 pathway-dependent neutrophil responses

Host defense against bacterial and fungal infections diminishes with age. In humans, impaired neutrophil responses are thought to contribute to this decline. However, it remains unclear whether neutrophil responses are also impaired in old mice. Here, we investigated neutrophil function in old mice,...

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Detalles Bibliográficos
Autores principales: Hornigold, Kirsti, Chu, Julia Y., Chetwynd, Stephen A., Machin, Polly A., Crossland, Laraine, Pantarelli, Chiara, Anderson, Karen E., Hawkins, Phillip T., Segonds-Pichon, Anne, Oxley, David, Welch, Heidi C. E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9450589/
https://www.ncbi.nlm.nih.gov/pubmed/36090969
http://dx.doi.org/10.3389/fimmu.2022.888415

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