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Comparing the clinical profile of non obese children with sleep apnea and snoring

Few studies in the literature have looked into the cardiovascular and metabolic effects of Obstructive Sleep Apnea Syndrome (OSAS) in children. OBJECTIVE: This study aims to evaluate the metabolic profile of non-obese children with OSAS. METHODS: Fifty-two children were enrolled in this study, 21 gi...

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Autores principales: de Oliveira Soares Stefanini, Daniele, de Barros, Emília Leite, Stefanini, Renato, de Cássia Pradella-Hallinan, Márcia Lurdes, Nagata Pignatari, Shirley Shizue, Fujita, Reginaldo Raimundo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9450707/
https://www.ncbi.nlm.nih.gov/pubmed/23108816
http://dx.doi.org/10.5935/1808-8694.20120004
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author de Oliveira Soares Stefanini, Daniele
de Barros, Emília Leite
Stefanini, Renato
de Cássia Pradella-Hallinan, Márcia Lurdes
Nagata Pignatari, Shirley Shizue
Fujita, Reginaldo Raimundo
author_facet de Oliveira Soares Stefanini, Daniele
de Barros, Emília Leite
Stefanini, Renato
de Cássia Pradella-Hallinan, Márcia Lurdes
Nagata Pignatari, Shirley Shizue
Fujita, Reginaldo Raimundo
author_sort de Oliveira Soares Stefanini, Daniele
collection PubMed
description Few studies in the literature have looked into the cardiovascular and metabolic effects of Obstructive Sleep Apnea Syndrome (OSAS) in children. OBJECTIVE: This study aims to evaluate the metabolic profile of non-obese children with OSAS. METHODS: Fifty-two children were enrolled in this study, 21 girls and 31 boys. Patients were divided into two groups: OSAS (28 children) and Snore (22 children) according to polysomnographic evaluation. All children were submitted to ENT examination, measurements of weight, height and blood pressure. Blood samples were tested for hemoglobin, hematocrit, fasting glucose, fasting insulin, triglycerides, total cholesterol, HDL, LDL, VLDL, TSH and T4. The gathered data sets were compared between groups and also within the OSAS group according to the severity of the syndrome. RESULTS: The children from both groups had no alterations in blood pressure levels. The results of the blood tests were normal for both groups. Results of hemoglobin, hematocrit, and HDL were all significantly higher in the Snore group when compared to the OSAS group; by their turn, VLDL levels were higher in the OSAS group. There was no statistical difference between the groups based on OSAS severity. CONCLUSION: Non-obese children with OSAS present no significant alterations in metabolic tests or blood pressure levels.
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spelling pubmed-94507072022-09-09 Comparing the clinical profile of non obese children with sleep apnea and snoring de Oliveira Soares Stefanini, Daniele de Barros, Emília Leite Stefanini, Renato de Cássia Pradella-Hallinan, Márcia Lurdes Nagata Pignatari, Shirley Shizue Fujita, Reginaldo Raimundo Braz J Otorhinolaryngol Original Article Few studies in the literature have looked into the cardiovascular and metabolic effects of Obstructive Sleep Apnea Syndrome (OSAS) in children. OBJECTIVE: This study aims to evaluate the metabolic profile of non-obese children with OSAS. METHODS: Fifty-two children were enrolled in this study, 21 girls and 31 boys. Patients were divided into two groups: OSAS (28 children) and Snore (22 children) according to polysomnographic evaluation. All children were submitted to ENT examination, measurements of weight, height and blood pressure. Blood samples were tested for hemoglobin, hematocrit, fasting glucose, fasting insulin, triglycerides, total cholesterol, HDL, LDL, VLDL, TSH and T4. The gathered data sets were compared between groups and also within the OSAS group according to the severity of the syndrome. RESULTS: The children from both groups had no alterations in blood pressure levels. The results of the blood tests were normal for both groups. Results of hemoglobin, hematocrit, and HDL were all significantly higher in the Snore group when compared to the OSAS group; by their turn, VLDL levels were higher in the OSAS group. There was no statistical difference between the groups based on OSAS severity. CONCLUSION: Non-obese children with OSAS present no significant alterations in metabolic tests or blood pressure levels. Elsevier 2015-11-20 /pmc/articles/PMC9450707/ /pubmed/23108816 http://dx.doi.org/10.5935/1808-8694.20120004 Text en . https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Original Article
de Oliveira Soares Stefanini, Daniele
de Barros, Emília Leite
Stefanini, Renato
de Cássia Pradella-Hallinan, Márcia Lurdes
Nagata Pignatari, Shirley Shizue
Fujita, Reginaldo Raimundo
Comparing the clinical profile of non obese children with sleep apnea and snoring
title Comparing the clinical profile of non obese children with sleep apnea and snoring
title_full Comparing the clinical profile of non obese children with sleep apnea and snoring
title_fullStr Comparing the clinical profile of non obese children with sleep apnea and snoring
title_full_unstemmed Comparing the clinical profile of non obese children with sleep apnea and snoring
title_short Comparing the clinical profile of non obese children with sleep apnea and snoring
title_sort comparing the clinical profile of non obese children with sleep apnea and snoring
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9450707/
https://www.ncbi.nlm.nih.gov/pubmed/23108816
http://dx.doi.org/10.5935/1808-8694.20120004
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