Inhibition of cGAS in Paraventricular Nucleus Attenuates Hypertensive Heart Injury Via Regulating Microglial Autophagy

Neuroinflammation in the cardiovascular center plays a critical role in the progression of hypertensive heart disease. And microglial autophagy is involved in the regulation of neuroinflammation. Cyclic GMP-AMP synthase (cGAS), a cytosolic DNA sensor, senses mitochondrial DNA (mtDNA) and regulates a...

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Detalles Bibliográficos
Autores principales: Han, Chengzhi, Qian, Xinyi, Ren, Xiaorong, Zhang, Shutian, Hu, Li, Li, Jingyao, Huang, Yijun, Huang, Renhui, Ooi, Kokwin, Lin, Hong, Xia, Chunmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9450841/
https://www.ncbi.nlm.nih.gov/pubmed/36070120
http://dx.doi.org/10.1007/s12035-022-02994-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9450841/
https://www.ncbi.nlm.nih.gov/pubmed/36070120
http://dx.doi.org/10.1007/s12035-022-02994-1

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