Adaptor SH3BGRL drives autophagy-mediated chemoresistance through promoting PIK3C3 translation and ATG12 stability in breast cancers

Acquired chemotherapy resistance is one of the main culprits in the relapse of breast cancer. But the underlying mechanism of chemotherapy resistance remains elusive. Here, we demonstrate that a small adaptor protein, SH3BGRL, is not only elevated in the majority of breast cancer patients but also h...

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Detalles Bibliográficos
Autores principales: Zhang, Shaoyang, Liu, Xiufeng, Abdulmomen Ali Mohammed, Saleh, Li, Hui, Cai, Wanhua, Guan, Wen, Liu, Daiyun, Wei, Yanli, Rong, Dade, Fang, Ying, Haider, Farhan, Lv, Haimei, Jin, Ziwei, Chen, Xiaomin, Mo, Zhuomao, Li, Lujie, Yang, Shulan, Wang, Haihe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9450985/
https://www.ncbi.nlm.nih.gov/pubmed/34870550
http://dx.doi.org/10.1080/15548627.2021.2002108

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