Polycystin-2 mediates mechanical tension-induced osteogenic differentiation of human adipose-derived stem cells by activating transcriptional co-activator with PDZ-binding motif

Human adipose-derived stem cells (hASCs) have multi-directional differentiation potential including osteogenic differentiation. Mechanical stimulation is thought to be a key regulator of bone remodeling and has been proved to promote osteogenic differentiation of mesenchymal stem cells. However, the...

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Detalles Bibliográficos
Autores principales: Wang, Liang, Lu, Yahui, Cai, Guanhui, Chen, Hongyu, Li, Gen, Liu, Luwei, Sun, Lian, Guan, Zhaolan, Sun, Wen, Zhao, Chunyang, Wang, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9450996/
https://www.ncbi.nlm.nih.gov/pubmed/36091380
http://dx.doi.org/10.3389/fphys.2022.917510

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