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The SREBP-dependent regulation of cyclin D1 coordinates cell proliferation and lipid synthesis
The sterol regulatory-element binding protein (SREBP) family of transcription factors regulates cholesterol, fatty acid, and triglyceride synthesis and metabolism. However, they are also targeted by the ubiquitin ligase Fbw7, a major tumor suppressor, suggesting that they could regulate cell growth....
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9451027/ https://www.ncbi.nlm.nih.gov/pubmed/36091143 http://dx.doi.org/10.3389/fonc.2022.942386 |