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Practical identifiability analysis of a mechanistic model for the time to distant metastatic relapse and its application to renal cell carcinoma

Distant metastasis-free survival (DMFS) curves are widely used in oncology. They are classically analyzed using the Kaplan-Meier estimator or agnostic statistical models from survival analysis. Here we report on a method to extract more information from DMFS curves using a mathematical model of prim...

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Detalles Bibliográficos
Autores principales: Álvarez-Arenas, Arturo, Souleyreau, Wilfried, Emanuelli, Andrea, Cooley, Lindsay S., Bernhard, Jean-Christophe, Bikfalvi, Andreas, Benzekry, Sebastien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9451098/
https://www.ncbi.nlm.nih.gov/pubmed/36007057
http://dx.doi.org/10.1371/journal.pcbi.1010444

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