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Practical identifiability analysis of a mechanistic model for the time to distant metastatic relapse and its application to renal cell carcinoma
Distant metastasis-free survival (DMFS) curves are widely used in oncology. They are classically analyzed using the Kaplan-Meier estimator or agnostic statistical models from survival analysis. Here we report on a method to extract more information from DMFS curves using a mathematical model of prim...
Autores principales: | Álvarez-Arenas, Arturo, Souleyreau, Wilfried, Emanuelli, Andrea, Cooley, Lindsay S., Bernhard, Jean-Christophe, Bikfalvi, Andreas, Benzekry, Sebastien |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9451098/ https://www.ncbi.nlm.nih.gov/pubmed/36007057 http://dx.doi.org/10.1371/journal.pcbi.1010444 |
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