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A Comparison of Murine PD-1 and PD-L1 Monoclonal Antibodies

Blockade of the PD-L1/PD-1 pathway has proven to be a broadly effective cancer immunotherapy. FDA-approved therapeutic monoclonal antibodies (mAbs) targeting the pathway have high affinity, blocking capacity, and low antibody effector activity. A number of rat antimouse mAbs have been used to model...

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Detalles Bibliográficos
Autores principales:	Bu, Melissa T., Yuan, Long, Klee, Alyssa N., Freeman, Gordon J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Mary Ann Liebert, Inc., publishers 2022
Materias:	Short Communications
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9451140/ https://www.ncbi.nlm.nih.gov/pubmed/35925787 http://dx.doi.org/10.1089/mab.2021.0068

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