Mutations in BCOR, a co-repressor of CRX/OTX2, are associated with early-onset retinal degeneration

Many transcription factors regulating the production, survival, and function of photoreceptor cells have been identified, but little is known about transcriptional co-regulators in retinal health and disease. Here, we show that BCL6 co-repressor (BCOR), a Polycomb repressive complex 1 factor mutated...

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Detalles Bibliográficos
Autores principales: Langouët, Maéva, Jolicoeur, Christine, Javed, Awais, Mattar, Pierre, Gearhart, Micah D., Daiger, Stephen P., Bertelsen, Mette, Tranebjærg, Lisbeth, Rendtorff, Nanna D., Grønskov, Karen, Jespersgaard, Catherine, Chen, Rui, Sun, Zixi, Li, Hui, Alirezaie, Najmeh, Majewski, Jacek, Bardwell, Vivian J., Sui, Ruifang, Koenekoop, Robert K., Cayouette, Michel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9451151/
https://www.ncbi.nlm.nih.gov/pubmed/36070393
http://dx.doi.org/10.1126/sciadv.abh2868

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