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A Rare Metastatic Primary Rectal Melanoma in a Geriatric Male

Primary rectal melanoma (PRM) is an uncommon malignancy whose etiology remains unknown. Most patients present with rectal bleeding. Distant metastasis is commonly seen in the lung and liver. The incidence rates for locoregional lymph node metastases on initial presentation are almost 60%. Histology...

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Autores principales: Ugonabo, Onyinye, Mohamed, Mujtaba, Ezeh, Ebubechukwu, Simmons, Joseph, Cuda, Jonathan, Ghavimi, Shima
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elmer Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9451565/
https://www.ncbi.nlm.nih.gov/pubmed/36128069
http://dx.doi.org/10.14740/jmc3929
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author Ugonabo, Onyinye
Mohamed, Mujtaba
Ezeh, Ebubechukwu
Simmons, Joseph
Cuda, Jonathan
Ghavimi, Shima
author_facet Ugonabo, Onyinye
Mohamed, Mujtaba
Ezeh, Ebubechukwu
Simmons, Joseph
Cuda, Jonathan
Ghavimi, Shima
author_sort Ugonabo, Onyinye
collection PubMed
description Primary rectal melanoma (PRM) is an uncommon malignancy whose etiology remains unknown. Most patients present with rectal bleeding. Distant metastasis is commonly seen in the lung and liver. The incidence rates for locoregional lymph node metastases on initial presentation are almost 60%. Histology and immunochemistry are useful and are the gold standard for diagnosis. The prognosis is very poor due to the late presentation of patients. Optimum surgical treatment remains controversial. Abdominoperineal resection was considered traditionally but over time, has been found to have no survival benefit. Current literature and studies, therefore, recommend wide local excision. The beneficial effects of chemotherapy versus radiotherapy use are still debatable. Herein, we discuss a case of a 72-year-old Caucasian male with rectal bleeding found to have metastasized PRM.
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spelling pubmed-94515652022-09-19 A Rare Metastatic Primary Rectal Melanoma in a Geriatric Male Ugonabo, Onyinye Mohamed, Mujtaba Ezeh, Ebubechukwu Simmons, Joseph Cuda, Jonathan Ghavimi, Shima J Med Cases Case Report Primary rectal melanoma (PRM) is an uncommon malignancy whose etiology remains unknown. Most patients present with rectal bleeding. Distant metastasis is commonly seen in the lung and liver. The incidence rates for locoregional lymph node metastases on initial presentation are almost 60%. Histology and immunochemistry are useful and are the gold standard for diagnosis. The prognosis is very poor due to the late presentation of patients. Optimum surgical treatment remains controversial. Abdominoperineal resection was considered traditionally but over time, has been found to have no survival benefit. Current literature and studies, therefore, recommend wide local excision. The beneficial effects of chemotherapy versus radiotherapy use are still debatable. Herein, we discuss a case of a 72-year-old Caucasian male with rectal bleeding found to have metastasized PRM. Elmer Press 2022-08 2022-08-19 /pmc/articles/PMC9451565/ /pubmed/36128069 http://dx.doi.org/10.14740/jmc3929 Text en Copyright 2022, Ugonabo et al. https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution Non-Commercial 4.0 International License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Ugonabo, Onyinye
Mohamed, Mujtaba
Ezeh, Ebubechukwu
Simmons, Joseph
Cuda, Jonathan
Ghavimi, Shima
A Rare Metastatic Primary Rectal Melanoma in a Geriatric Male
title A Rare Metastatic Primary Rectal Melanoma in a Geriatric Male
title_full A Rare Metastatic Primary Rectal Melanoma in a Geriatric Male
title_fullStr A Rare Metastatic Primary Rectal Melanoma in a Geriatric Male
title_full_unstemmed A Rare Metastatic Primary Rectal Melanoma in a Geriatric Male
title_short A Rare Metastatic Primary Rectal Melanoma in a Geriatric Male
title_sort rare metastatic primary rectal melanoma in a geriatric male
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9451565/
https://www.ncbi.nlm.nih.gov/pubmed/36128069
http://dx.doi.org/10.14740/jmc3929
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