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A Rare Metastatic Primary Rectal Melanoma in a Geriatric Male
Primary rectal melanoma (PRM) is an uncommon malignancy whose etiology remains unknown. Most patients present with rectal bleeding. Distant metastasis is commonly seen in the lung and liver. The incidence rates for locoregional lymph node metastases on initial presentation are almost 60%. Histology...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elmer Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9451565/ https://www.ncbi.nlm.nih.gov/pubmed/36128069 http://dx.doi.org/10.14740/jmc3929 |
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author | Ugonabo, Onyinye Mohamed, Mujtaba Ezeh, Ebubechukwu Simmons, Joseph Cuda, Jonathan Ghavimi, Shima |
author_facet | Ugonabo, Onyinye Mohamed, Mujtaba Ezeh, Ebubechukwu Simmons, Joseph Cuda, Jonathan Ghavimi, Shima |
author_sort | Ugonabo, Onyinye |
collection | PubMed |
description | Primary rectal melanoma (PRM) is an uncommon malignancy whose etiology remains unknown. Most patients present with rectal bleeding. Distant metastasis is commonly seen in the lung and liver. The incidence rates for locoregional lymph node metastases on initial presentation are almost 60%. Histology and immunochemistry are useful and are the gold standard for diagnosis. The prognosis is very poor due to the late presentation of patients. Optimum surgical treatment remains controversial. Abdominoperineal resection was considered traditionally but over time, has been found to have no survival benefit. Current literature and studies, therefore, recommend wide local excision. The beneficial effects of chemotherapy versus radiotherapy use are still debatable. Herein, we discuss a case of a 72-year-old Caucasian male with rectal bleeding found to have metastasized PRM. |
format | Online Article Text |
id | pubmed-9451565 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Elmer Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-94515652022-09-19 A Rare Metastatic Primary Rectal Melanoma in a Geriatric Male Ugonabo, Onyinye Mohamed, Mujtaba Ezeh, Ebubechukwu Simmons, Joseph Cuda, Jonathan Ghavimi, Shima J Med Cases Case Report Primary rectal melanoma (PRM) is an uncommon malignancy whose etiology remains unknown. Most patients present with rectal bleeding. Distant metastasis is commonly seen in the lung and liver. The incidence rates for locoregional lymph node metastases on initial presentation are almost 60%. Histology and immunochemistry are useful and are the gold standard for diagnosis. The prognosis is very poor due to the late presentation of patients. Optimum surgical treatment remains controversial. Abdominoperineal resection was considered traditionally but over time, has been found to have no survival benefit. Current literature and studies, therefore, recommend wide local excision. The beneficial effects of chemotherapy versus radiotherapy use are still debatable. Herein, we discuss a case of a 72-year-old Caucasian male with rectal bleeding found to have metastasized PRM. Elmer Press 2022-08 2022-08-19 /pmc/articles/PMC9451565/ /pubmed/36128069 http://dx.doi.org/10.14740/jmc3929 Text en Copyright 2022, Ugonabo et al. https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution Non-Commercial 4.0 International License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Ugonabo, Onyinye Mohamed, Mujtaba Ezeh, Ebubechukwu Simmons, Joseph Cuda, Jonathan Ghavimi, Shima A Rare Metastatic Primary Rectal Melanoma in a Geriatric Male |
title | A Rare Metastatic Primary Rectal Melanoma in a Geriatric Male |
title_full | A Rare Metastatic Primary Rectal Melanoma in a Geriatric Male |
title_fullStr | A Rare Metastatic Primary Rectal Melanoma in a Geriatric Male |
title_full_unstemmed | A Rare Metastatic Primary Rectal Melanoma in a Geriatric Male |
title_short | A Rare Metastatic Primary Rectal Melanoma in a Geriatric Male |
title_sort | rare metastatic primary rectal melanoma in a geriatric male |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9451565/ https://www.ncbi.nlm.nih.gov/pubmed/36128069 http://dx.doi.org/10.14740/jmc3929 |
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