Inhibition of platelet-derived growth factor pathway suppresses tubulointerstitial injury in renal congestion

Increased central venous pressure in congestive heart failure is responsible for renal dysfunction, which is mediated by renal venous congestion. Pericyte detachment from capillaries after renal congestion might trigger renal fibrogenesis via pericyte-myofibroblast transition (PMT). Platelet-derived...

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Detalles Bibliográficos
Autores principales: Matsuki, Takuma, Hirose, Takuo, Ohsaki, Yusuke, Shimada, Satoshi, Endo, Akari, Ito, Hiroki, Takahashi, Chika, Yamakoshi, Seiko, Oba-Yabana, Ikuko, Anan, Go, Kato, Toshiko, Tajima, Ryo, Nakayama, Shingo, Kimura, Tomoyoshi, Nakamura, Hannah, Tani, Junichi, Takahashi, Kazuhiro, Kure, Shigeo, Mori, Takefumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9451920/
https://www.ncbi.nlm.nih.gov/pubmed/35983805
http://dx.doi.org/10.1097/HJH.0000000000003191

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