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Profile and Outcome of Management of Brain Tumours in Kaduna Northwestern Nigeria

OBJECTIVE: Tumours of the brain are a rare occurrence accounting for approximately 2% of all neoplasms in adults. Few studies have been done in Nigeria on the profile of brain tumours. The aim of this study is to determine the profile of brain tumours in general and determine the change in Kanofsky...

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Autores principales: Danjuma, Sale, Dauda, Happy Amos, Kene, Aghadi Ifeanyi, Akau, Kache Stephen, Jinjiri, Ismail Nasiru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Neurosurgical Society 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9452380/
https://www.ncbi.nlm.nih.gov/pubmed/36070965
http://dx.doi.org/10.3340/jkns.2021.0071
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author Danjuma, Sale
Dauda, Happy Amos
Kene, Aghadi Ifeanyi
Akau, Kache Stephen
Jinjiri, Ismail Nasiru
author_facet Danjuma, Sale
Dauda, Happy Amos
Kene, Aghadi Ifeanyi
Akau, Kache Stephen
Jinjiri, Ismail Nasiru
author_sort Danjuma, Sale
collection PubMed
description OBJECTIVE: Tumours of the brain are a rare occurrence accounting for approximately 2% of all neoplasms in adults. Few studies have been done in Nigeria on the profile of brain tumours. The aim of this study is to determine the profile of brain tumours in general and determine the change in Kanofsky Performance Score (KPS) after treatment. METHODS: This is a prospective hospital-based study in Kaduna. All consecutive patients over 18 years of age with diagnosis of brain tumours from January 2016 to December 2019 were included in the study. Demographic and clinical data was collected using a proforma during the study. Patients who received treatment were followed up for 12 months. The primary outcome data was the difference in the quality of life as measured by KPS at the point of first contact and at 1-month after treatment and at 12-month follow up. Data obtained was analysed with SPSS version 25.0 for Windows. Descriptive statistics was done to determine the profile. Paired t-test at 95% confidence interval was done to check for significant correlation between the mean KPS. RESULTS: A total of 39 consecutive patients were included in the study. There was a slight male preponderance with a M : F of 1.17 : 1. Meningioma and metastasis were more common in females while gliomas and pituitary tumours were more common in males. The mean age of patients was 49.8 years and standard deviation of 11.8 years. Pituitary tumours were the most common tumours. The most common location of the tumour was frontal lobe followed by the pituitary gland. The mean duration of symptoms before neurosurgical consultation was 38 weeks. The most common presenting symptoms of patient with brain tumour was headache. The quality of life improve compare to the baseline in 81% of patient at discharge and at 1 year follow up. The overall mortality rate was 25.6%. CONCLUSION: The most common brain tumour in our study is pituitary tumour. Most patients present late. The most common presenting symptoms is headache. There is significant improvement in the KPS of patients following treatment. The overall mortality rate at 1-year post treatment is 25.6%.
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spelling pubmed-94523802022-09-14 Profile and Outcome of Management of Brain Tumours in Kaduna Northwestern Nigeria Danjuma, Sale Dauda, Happy Amos Kene, Aghadi Ifeanyi Akau, Kache Stephen Jinjiri, Ismail Nasiru J Korean Neurosurg Soc Clinical Article OBJECTIVE: Tumours of the brain are a rare occurrence accounting for approximately 2% of all neoplasms in adults. Few studies have been done in Nigeria on the profile of brain tumours. The aim of this study is to determine the profile of brain tumours in general and determine the change in Kanofsky Performance Score (KPS) after treatment. METHODS: This is a prospective hospital-based study in Kaduna. All consecutive patients over 18 years of age with diagnosis of brain tumours from January 2016 to December 2019 were included in the study. Demographic and clinical data was collected using a proforma during the study. Patients who received treatment were followed up for 12 months. The primary outcome data was the difference in the quality of life as measured by KPS at the point of first contact and at 1-month after treatment and at 12-month follow up. Data obtained was analysed with SPSS version 25.0 for Windows. Descriptive statistics was done to determine the profile. Paired t-test at 95% confidence interval was done to check for significant correlation between the mean KPS. RESULTS: A total of 39 consecutive patients were included in the study. There was a slight male preponderance with a M : F of 1.17 : 1. Meningioma and metastasis were more common in females while gliomas and pituitary tumours were more common in males. The mean age of patients was 49.8 years and standard deviation of 11.8 years. Pituitary tumours were the most common tumours. The most common location of the tumour was frontal lobe followed by the pituitary gland. The mean duration of symptoms before neurosurgical consultation was 38 weeks. The most common presenting symptoms of patient with brain tumour was headache. The quality of life improve compare to the baseline in 81% of patient at discharge and at 1 year follow up. The overall mortality rate was 25.6%. CONCLUSION: The most common brain tumour in our study is pituitary tumour. Most patients present late. The most common presenting symptoms is headache. There is significant improvement in the KPS of patients following treatment. The overall mortality rate at 1-year post treatment is 25.6%. Korean Neurosurgical Society 2022-09 2022-09-01 /pmc/articles/PMC9452380/ /pubmed/36070965 http://dx.doi.org/10.3340/jkns.2021.0071 Text en Copyright © 2022 The Korean Neurosurgical Society https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0 (https://creativecommons.org/licenses/by-nc/4.0/) ) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Clinical Article
Danjuma, Sale
Dauda, Happy Amos
Kene, Aghadi Ifeanyi
Akau, Kache Stephen
Jinjiri, Ismail Nasiru
Profile and Outcome of Management of Brain Tumours in Kaduna Northwestern Nigeria
title Profile and Outcome of Management of Brain Tumours in Kaduna Northwestern Nigeria
title_full Profile and Outcome of Management of Brain Tumours in Kaduna Northwestern Nigeria
title_fullStr Profile and Outcome of Management of Brain Tumours in Kaduna Northwestern Nigeria
title_full_unstemmed Profile and Outcome of Management of Brain Tumours in Kaduna Northwestern Nigeria
title_short Profile and Outcome of Management of Brain Tumours in Kaduna Northwestern Nigeria
title_sort profile and outcome of management of brain tumours in kaduna northwestern nigeria
topic Clinical Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9452380/
https://www.ncbi.nlm.nih.gov/pubmed/36070965
http://dx.doi.org/10.3340/jkns.2021.0071
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