Regulator of calcineurin 1 deletion attenuates mitochondrial dysfunction and apoptosis in acute kidney injury through JNK/Mff signaling pathway

Ischemia-reperfusion (I/R) induced acute kidney injury (AKI), characterized by excessive mitochondrial damage and cell apoptosis, remains a clinical challenge. Recent studies suggest that regulator of calcineurin 1 (RCAN1) regulates mitochondrial function in different cell types, but the underlying...

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Detalles Bibliográficos
Autores principales: Xiao, Jing-Jie, Liu, Qing, Li, Ying, Peng, Fang-Fang, Wang, Shan, Zhang, Zhihan, Liu, Hui, Yu, Hong, Tao, Shengxiang, Zhang, Bai-Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9452577/
https://www.ncbi.nlm.nih.gov/pubmed/36071051
http://dx.doi.org/10.1038/s41419-022-05220-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9452577/
https://www.ncbi.nlm.nih.gov/pubmed/36071051
http://dx.doi.org/10.1038/s41419-022-05220-x

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