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Elucidation of the di-c-glycosylation steps during biosynthesis of the antitumor antibiotic, kidamycin

Kidamycins belong to the pluramycin family of antitumor antibiotics that contain di-C-glycosylated angucycline. Owing to its interesting biological activity, several synthetic derivatives of kidamycins are currently being developed. However, the synthesis of these complex structural compounds with u...

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Detalles Bibliográficos
Autores principales: Heo, Kyung Taek, Lee, Byeongsan, Jang, Jae-Hyuk, Hong, Young-Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9452638/
https://www.ncbi.nlm.nih.gov/pubmed/36091425
http://dx.doi.org/10.3389/fbioe.2022.985696

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