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Elucidation of the di-c-glycosylation steps during biosynthesis of the antitumor antibiotic, kidamycin
Kidamycins belong to the pluramycin family of antitumor antibiotics that contain di-C-glycosylated angucycline. Owing to its interesting biological activity, several synthetic derivatives of kidamycins are currently being developed. However, the synthesis of these complex structural compounds with u...
Autores principales: | Heo, Kyung Taek, Lee, Byeongsan, Jang, Jae-Hyuk, Hong, Young-Soo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9452638/ https://www.ncbi.nlm.nih.gov/pubmed/36091425 http://dx.doi.org/10.3389/fbioe.2022.985696 |
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