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Evaluating a therapeutic window for precision medicine by integrating genomic profiles and p53 network dynamics
The response variation to anti-cancer drugs originates from complex intracellular network dynamics of cancer. Such dynamic networks present challenges to determining optimal drug targets and stratifying cancer patients for precision medicine, although several cancer genome studies provided insights...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9452682/ https://www.ncbi.nlm.nih.gov/pubmed/36071176 http://dx.doi.org/10.1038/s42003-022-03872-1 |