Suppression of FOXP3 expression by the AP-1 family transcription factor BATF3 requires partnering with IRF4

FOXP3 is the lineage-defining transcription factor for Tregs, a cell type critical to immune tolerance, but the mechanisms that control FOXP3 expression in Tregs remain incompletely defined, particularly as it relates to signals downstream of TCR and CD28 signaling. Herein, we studied the role of IR...

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Detalles Bibliográficos
Autores principales: Arnold, Preston R., Wen, Mou, Zhang, Lei, Ying, Yuanlin, Xiao, Xiang, Chu, Xiufeng, Wang, Guangchuan, Zhang, Xiaolong, Mao, Zhuyun, Zhang, Aijun, Hamilton, Dale J., Chen, Wenhao, Li, Xian C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9452699/
https://www.ncbi.nlm.nih.gov/pubmed/36090981
http://dx.doi.org/10.3389/fimmu.2022.966364

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