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Targeting trafficking as a therapeutic avenue for misfolded GPCRs leading to endocrine diseases
G protein-coupled receptors (GPCRs) are plasma membrane proteins associated with an array of functions. Mutations in these receptors lead to a number of genetic diseases, including diseases involving the endocrine system. A particular subset of loss-of-function mutant GPCRs are misfolded receptors u...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9452723/ https://www.ncbi.nlm.nih.gov/pubmed/36093106 http://dx.doi.org/10.3389/fendo.2022.934685 |