Strategies to safely target widely expressed soluble adenylyl cyclase for contraception

In humans, the prototypical second messenger cyclic AMP is produced by 10 adenylyl cyclase isoforms, which are divided into two classes. Nine isoforms are G protein coupled transmembrane adenylyl cyclases (tmACs; ADCY1-9) and the 10th is the bicarbonate regulated soluble adenylyl cyclase (sAC; ADCY1...

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Detalles Bibliográficos
Autores principales: Ferreira, Jacob, Levin, Lonny R., Buck, Jochen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9452739/
https://www.ncbi.nlm.nih.gov/pubmed/36091839
http://dx.doi.org/10.3389/fphar.2022.953903

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9452739/
https://www.ncbi.nlm.nih.gov/pubmed/36091839
http://dx.doi.org/10.3389/fphar.2022.953903

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