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Strategies to safely target widely expressed soluble adenylyl cyclase for contraception
In humans, the prototypical second messenger cyclic AMP is produced by 10 adenylyl cyclase isoforms, which are divided into two classes. Nine isoforms are G protein coupled transmembrane adenylyl cyclases (tmACs; ADCY1-9) and the 10th is the bicarbonate regulated soluble adenylyl cyclase (sAC; ADCY1...
Autores principales: | Ferreira, Jacob, Levin, Lonny R., Buck, Jochen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9452739/ https://www.ncbi.nlm.nih.gov/pubmed/36091839 http://dx.doi.org/10.3389/fphar.2022.953903 |
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