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PLK1-mediated phosphorylation of PPIL2 regulates HR via CtIP

Homologous recombination (HR) is an error-free DNA double-strand break (DSB) repair pathway, which safeguards genome integrity and cell viability. Human C-terminal binding protein (CtBP)—interacting protein (CtIP) is a central regulator of the pathway which initiates the DNA end resection in HR. Ubi...

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Detalles Bibliográficos
Autores principales:	Qiu, Zhiyu, Hao, Shuailin, Song, Shikai, Zhang, Ruiling, Yan, Tingyu, Lu, Zhifang, Wang, Hailong, Jia, Zongchao, Zheng, Jimin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9452783/ https://www.ncbi.nlm.nih.gov/pubmed/36092721 http://dx.doi.org/10.3389/fcell.2022.902403

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