Sodium para-aminosalicylic acid ameliorates lead-induced hippocampal neuronal apoptosis by suppressing the activation of the IP(3)R-Ca(2+)-ASK1-p38 signaling pathway

Lead (Pb) is a naturally occurring heavy metal, which can damage the brain and affect learning and memory. Sodium para-aminosalicylic acid (PAS-Na), a non-steroidal anti-inflammatory drug, can readily cross the blood-brain barrier. Our previous studies have found that PAS-Na alleviated Pb-induced hi...

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Detalles Bibliográficos
Autores principales: Li, Zhao-cong, Wang, Lei-lei, Zhao, Yue-song, Peng, Dong-jie, Chen, Jing, Jiang, Si-yang, Zhao, Lin, Aschner, Michael, Li, Shao-jun, Jiang, Yue-ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9452829/
https://www.ncbi.nlm.nih.gov/pubmed/36068756
http://dx.doi.org/10.1016/j.ecoenv.2022.113829

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9452829/
https://www.ncbi.nlm.nih.gov/pubmed/36068756
http://dx.doi.org/10.1016/j.ecoenv.2022.113829

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