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Breast MRI Tumor Automatic Segmentation and Triple-Negative Breast Cancer Discrimination Algorithm Based on Deep Learning

BACKGROUND: Breast cancer is a kind of cancer that starts in the epithelial tissue of the breast. Breast cancer has been on the rise in recent years, with a younger generation developing the disease. Magnetic resonance imaging (MRI) plays an important role in breast tumor detection and treatment pla...

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Autores principales: Guo, Ying-Ying, Huang, Yin-Hui, Wang, Yi, Huang, Jing, Lai, Qing-Quan, Li, Yuan-Zhe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9453096/
https://www.ncbi.nlm.nih.gov/pubmed/36092784
http://dx.doi.org/10.1155/2022/2541358
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author Guo, Ying-Ying
Huang, Yin-Hui
Wang, Yi
Huang, Jing
Lai, Qing-Quan
Li, Yuan-Zhe
author_facet Guo, Ying-Ying
Huang, Yin-Hui
Wang, Yi
Huang, Jing
Lai, Qing-Quan
Li, Yuan-Zhe
author_sort Guo, Ying-Ying
collection PubMed
description BACKGROUND: Breast cancer is a kind of cancer that starts in the epithelial tissue of the breast. Breast cancer has been on the rise in recent years, with a younger generation developing the disease. Magnetic resonance imaging (MRI) plays an important role in breast tumor detection and treatment planning in today's clinical practice. As manual segmentation grows more time-consuming and the observed topic becomes more diversified, automated segmentation becomes more appealing. Methodology. For MRI breast tumor segmentation, we propose a CNN-SVM network. The labels from the trained convolutional neural network are output using a support vector machine in this technique. During the testing phase, the convolutional neural network's labeled output, as well as the test grayscale picture, is passed to the SVM classifier for accurate segmentation. RESULTS: We tested on the collected breast tumor dataset and found that our proposed combined CNN-SVM network achieved 0.93, 0.95, and 0.92 on DSC coefficient, PPV, and sensitivity index, respectively. We also compare with the segmentation frameworks of other papers, and the comparison results prove that our CNN-SVM network performs better and can accurately segment breast tumors. CONCLUSION: Our proposed CNN-SVM combined network achieves good segmentation results on the breast tumor dataset. The method can adapt to the differences in breast tumors and segment breast tumors accurately and efficiently. It is of great significance for identifying triple-negative breast cancer in the future.
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spelling pubmed-94530962022-09-09 Breast MRI Tumor Automatic Segmentation and Triple-Negative Breast Cancer Discrimination Algorithm Based on Deep Learning Guo, Ying-Ying Huang, Yin-Hui Wang, Yi Huang, Jing Lai, Qing-Quan Li, Yuan-Zhe Comput Math Methods Med Research Article BACKGROUND: Breast cancer is a kind of cancer that starts in the epithelial tissue of the breast. Breast cancer has been on the rise in recent years, with a younger generation developing the disease. Magnetic resonance imaging (MRI) plays an important role in breast tumor detection and treatment planning in today's clinical practice. As manual segmentation grows more time-consuming and the observed topic becomes more diversified, automated segmentation becomes more appealing. Methodology. For MRI breast tumor segmentation, we propose a CNN-SVM network. The labels from the trained convolutional neural network are output using a support vector machine in this technique. During the testing phase, the convolutional neural network's labeled output, as well as the test grayscale picture, is passed to the SVM classifier for accurate segmentation. RESULTS: We tested on the collected breast tumor dataset and found that our proposed combined CNN-SVM network achieved 0.93, 0.95, and 0.92 on DSC coefficient, PPV, and sensitivity index, respectively. We also compare with the segmentation frameworks of other papers, and the comparison results prove that our CNN-SVM network performs better and can accurately segment breast tumors. CONCLUSION: Our proposed CNN-SVM combined network achieves good segmentation results on the breast tumor dataset. The method can adapt to the differences in breast tumors and segment breast tumors accurately and efficiently. It is of great significance for identifying triple-negative breast cancer in the future. Hindawi 2022-08-31 /pmc/articles/PMC9453096/ /pubmed/36092784 http://dx.doi.org/10.1155/2022/2541358 Text en Copyright © 2022 Ying-Ying Guo et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Guo, Ying-Ying
Huang, Yin-Hui
Wang, Yi
Huang, Jing
Lai, Qing-Quan
Li, Yuan-Zhe
Breast MRI Tumor Automatic Segmentation and Triple-Negative Breast Cancer Discrimination Algorithm Based on Deep Learning
title Breast MRI Tumor Automatic Segmentation and Triple-Negative Breast Cancer Discrimination Algorithm Based on Deep Learning
title_full Breast MRI Tumor Automatic Segmentation and Triple-Negative Breast Cancer Discrimination Algorithm Based on Deep Learning
title_fullStr Breast MRI Tumor Automatic Segmentation and Triple-Negative Breast Cancer Discrimination Algorithm Based on Deep Learning
title_full_unstemmed Breast MRI Tumor Automatic Segmentation and Triple-Negative Breast Cancer Discrimination Algorithm Based on Deep Learning
title_short Breast MRI Tumor Automatic Segmentation and Triple-Negative Breast Cancer Discrimination Algorithm Based on Deep Learning
title_sort breast mri tumor automatic segmentation and triple-negative breast cancer discrimination algorithm based on deep learning
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9453096/
https://www.ncbi.nlm.nih.gov/pubmed/36092784
http://dx.doi.org/10.1155/2022/2541358
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