Cargando…

CpG Oligodeoxynucleotides Inhibit RANKL-Induced Osteoclast Formation by Upregulating A20 Deubiquitinase in RAW 264.7 Cells

OBJECTIVE: Activation of toll-like receptor 9 (TLR9) has been proposed to play an inhibitory role in RANKL-induced osteoclastogenesis. A20 deubiquitinase has been found to be related to bone loss. This study investigated the role of CpG oligodeoxynucleotides (CpG-ODNs) through regulation of A20 deub...

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, Seong-Kyu, Choe, Jung-Yoon, Park, Ki-Yeun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9453122/
https://www.ncbi.nlm.nih.gov/pubmed/36091665
http://dx.doi.org/10.1155/2022/5255935