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Pancreatic transplant surgery and stem cell therapy: Finding the balance between therapeutic advances and ethical principles

The latest achievements in the field of pancreas transplantation and stem cell therapy require an effort by the scientific community to clarify the ethical implications of pioneering treatments, often characterized by high complexity from a surgical point of view, due to transplantation of multiple...

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Autores principales: Padovano, Martina, Scopetti, Matteo, Manetti, Federico, Morena, Donato, Radaelli, Davide, D’Errico, Stefano, Di Fazio, Nicola, Frati, Paola, Fineschi, Vittorio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9453273/
https://www.ncbi.nlm.nih.gov/pubmed/36157914
http://dx.doi.org/10.4252/wjsc.v14.i8.577
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author Padovano, Martina
Scopetti, Matteo
Manetti, Federico
Morena, Donato
Radaelli, Davide
D’Errico, Stefano
Di Fazio, Nicola
Frati, Paola
Fineschi, Vittorio
author_facet Padovano, Martina
Scopetti, Matteo
Manetti, Federico
Morena, Donato
Radaelli, Davide
D’Errico, Stefano
Di Fazio, Nicola
Frati, Paola
Fineschi, Vittorio
author_sort Padovano, Martina
collection PubMed
description The latest achievements in the field of pancreas transplantation and stem cell therapy require an effort by the scientific community to clarify the ethical implications of pioneering treatments, often characterized by high complexity from a surgical point of view, due to transplantation of multiple organs at the same time or at different times, and from an immunological point of view for stem cell therapy. The fundamental value in the field of organ transplants is, of course, a solidarity principle, namely that of protecting the health and life of people for whom transplantation is a condition of functional recovery, or even of survival. The nature of this value is that of a concept to which the legal discipline of transplants entrusts its own ethical dignity and for which it has ensured a constitutional recognition in different systems. The general principle of respect for human life, both of the donor and of the recipient, evokes the need not to put oneself and one’s neighbor in dangerous conditions. The present ethical reflection aims to find a balance between the latest therapeutic advances and several concepts including the idea of the person, the respect due to the dead, the voluntary nature of the donation and the consent to the same, the gratuitousness of the donation, the scientific progress and the development of surgical techniques, and the policies of health promotion.
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spelling pubmed-94532732022-09-23 Pancreatic transplant surgery and stem cell therapy: Finding the balance between therapeutic advances and ethical principles Padovano, Martina Scopetti, Matteo Manetti, Federico Morena, Donato Radaelli, Davide D’Errico, Stefano Di Fazio, Nicola Frati, Paola Fineschi, Vittorio World J Stem Cells Opinion Review The latest achievements in the field of pancreas transplantation and stem cell therapy require an effort by the scientific community to clarify the ethical implications of pioneering treatments, often characterized by high complexity from a surgical point of view, due to transplantation of multiple organs at the same time or at different times, and from an immunological point of view for stem cell therapy. The fundamental value in the field of organ transplants is, of course, a solidarity principle, namely that of protecting the health and life of people for whom transplantation is a condition of functional recovery, or even of survival. The nature of this value is that of a concept to which the legal discipline of transplants entrusts its own ethical dignity and for which it has ensured a constitutional recognition in different systems. The general principle of respect for human life, both of the donor and of the recipient, evokes the need not to put oneself and one’s neighbor in dangerous conditions. The present ethical reflection aims to find a balance between the latest therapeutic advances and several concepts including the idea of the person, the respect due to the dead, the voluntary nature of the donation and the consent to the same, the gratuitousness of the donation, the scientific progress and the development of surgical techniques, and the policies of health promotion. Baishideng Publishing Group Inc 2022-08-26 2022-08-26 /pmc/articles/PMC9453273/ /pubmed/36157914 http://dx.doi.org/10.4252/wjsc.v14.i8.577 Text en ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. https://creativecommons.org/licenses/by-nc/4.0/This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
spellingShingle Opinion Review
Padovano, Martina
Scopetti, Matteo
Manetti, Federico
Morena, Donato
Radaelli, Davide
D’Errico, Stefano
Di Fazio, Nicola
Frati, Paola
Fineschi, Vittorio
Pancreatic transplant surgery and stem cell therapy: Finding the balance between therapeutic advances and ethical principles
title Pancreatic transplant surgery and stem cell therapy: Finding the balance between therapeutic advances and ethical principles
title_full Pancreatic transplant surgery and stem cell therapy: Finding the balance between therapeutic advances and ethical principles
title_fullStr Pancreatic transplant surgery and stem cell therapy: Finding the balance between therapeutic advances and ethical principles
title_full_unstemmed Pancreatic transplant surgery and stem cell therapy: Finding the balance between therapeutic advances and ethical principles
title_short Pancreatic transplant surgery and stem cell therapy: Finding the balance between therapeutic advances and ethical principles
title_sort pancreatic transplant surgery and stem cell therapy: finding the balance between therapeutic advances and ethical principles
topic Opinion Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9453273/
https://www.ncbi.nlm.nih.gov/pubmed/36157914
http://dx.doi.org/10.4252/wjsc.v14.i8.577
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